Capricor Therapeutics (CAPR) had the highest return in April 2020 by a small-cap US stock, returning 488.2%.

ASSET	MONTH	% RETURN
Capricor Therapeutics (CAPR)	April 2020	488.24%
Vital Energy (VTLE)	April 2020	186.84%
Bit Digital (BTBT)	April 2020	174.07%
NGL Energy Partners (NGL)	April 2020	156.35%
Arcturus Therapeutics (ARCT)	April 2020	153.49%
Mesoblast (MESO)	April 2020	135.02%
SandRidge Energy (SD)	April 2020	123.58%
Summit Midstream (SMC)	April 2020	113.11%
Domo (DOMO)	April 2020	107.36%
Talos Energy (TALO)	April 2020	102.31%
BioCryst Pharmaceuticals (BCRX)	April 2020	100.51%
Core Laboratories (CLB)	April 2020	96.69%
Kosmos Energy (KOS)	April 2020	96.43%
Ellington Financial (EFC)	April 2020	95.69%
Alpha and Omega Semiconductor (AOSL)	April 2020	93.72%
Arcus Biosciences (RCUS)	April 2020	91.38%
Liberty Oilfield Services (LBRT)	April 2020	90.33%
Replimune (REPL)	April 2020	88.63%
Build-A-Bear Workshop (BBW)	April 2020	86.76%
Calumet Specialty Products Partners (CLMT)	April 2020	84.76%
ProPetro (PUMP)	April 2020	84.35%
Jack In The Box (JACK)	April 2020	82.56%
Oceaneering International (OII)	April 2020	80.35%
Denison Mines (DNN)	April 2020	78.54%
PlayAGS (AGS)	April 2020	77.73%

Small-cap stocks are treated as having a market cap between $300M and $2B.