Regencell Bioscience (RGC) has had the highest return this year by a US stock, returning 4,073.2%.

ASSET	YEAR	% RETURN
Regencell Bioscience (RGC)	2025	4,073.23%
Mobile Global Esports (MGAM)	2025	1,650%
Asset Entities Inc Class B Common Stock (ASST)	2025	1,438%
Diginex Limited Ordinary Shares (DGNX)	2025	1,250%
Janover Inc Common Stock (JNVR)	2025	1,097.66%
Webull Corporation Warrants (BULLW)	2025	857.15%
Oncology Institute (TOI)	2025	854.25%
HCM II Acquisition (HONDW)	2025	759.4%
Oncology Institute (TOIIW)	2025	732.14%
Splash Beverage Group, Inc WT (SBEV.WT)	2025	650%
Protagenic Therapeutics (PTIX)	2025	561.63%
Top KingWin (WAI)	2025	554.97%
Aimfinity Investment Corp I Warrant (AIMAW)	2025	542.86%
TMC the metals company Inc Warrants (TMCWW)	2025	502.64%
Marblegate Acquisition Corp Warrant (GATEW)	2025	466.67%
Dominari (DOMH)	2025	464.94%
error (ZVZZT)	2025	464.54%
Global Interactive Technologies (GITS)	2025	457.22%
Oriental Culture Holding (OCG)	2025	453.78%
NETCLASS TECHNOLOGY INC Class A Ordinary Shares (NTCL)	2025	440.75%
Yoshiharu Global (YOSH)	2025	393.79%
Regulus Therapeutics (RGLS)	2025	390.63%
Webull Corporation Incentive Warrant (BULLZ)	2025	388.89%
DatChat Inc Series A Warrant (DATSW)	2025	371.74%
Cohen Circle Acquisition Corp I Warrant (CCIRW)	2025	345.83%