XORTX Therapeutics (XRTX) had the highest return in Q3 2021 by a US stock, returning 5,323,869.8%.

ASSET	QUARTER	% RETURN
XORTX Therapeutics (XRTX)	Q3 2021	5,323,869.78%
Guardforce AI (GFAI)	Q3 2021	743,561.97%
Synergy CHC Corp Common Stock (SNYR)	Q3 2021	8,471.43%
Mega Matrix (MPU)	Q3 2021	476.16%
ATIF (ZBAI)	Q3 2021	394.51%
Aehr Test Systems (AEHR)	Q3 2021	391.01%
Next Technology (NXTT)	Q3 2021	302.95%
Myseum (MYSE)	Q3 2021	245.57%
Nukkleus (NUKK)	Q3 2021	233.33%
Intelligent Protection Management (IPM)	Q3 2021	225.23%
Mediaco (MDIA)	Q3 2021	224.25%
Fulcrum Therapeutics (FULC)	Q3 2021	172.3%
REalloys (ALOY)	Q3 2021	156.41%
Upstart Holdings (UPST)	Q3 2021	151.14%
Cypherpunk Technologies (CYPH)	Q3 2021	146.01%
ENvue Medical (FEED)	Q3 2021	134.09%
TROOPS (TROO)	Q3 2021	130.61%
Sphere 3D (ANY)	Q3 2021	128.46%
Ramaco Resources (METC)	Q3 2021	124.63%
Tianci International, Inc Common Stock (CIIT)	Q3 2021	117.67%
Arqit Quantum (ARQQ)	Q3 2021	102.52%
Invivyd (IVVD)	Q3 2021	101.14%
SandRidge Energy (SD)	Q3 2021	98.93%
Standard Lithium (SLI)	Q3 2021	96.85%
Hut 8 Corp Common Stock (HUT)	Q3 2021	95.35%