Azitra (AZTR) had the highest return between 2019 and 2023 by a US stock, returning 3,285,614.3%.

ASSET	YEARS	% RETURN
Azitra (AZTR)	2019-2023	3,285,614.29%
Brera Holdings PLC Class B Ordinary Shares (BREA)	2019-2023	1,311,900%
NioCorp Developments Ltd Common Stock (NB)	2019-2023	637,900%
Integra Resources (ITRG)	2019-2023	264,900%
MDxHealth SA ADR (MDXH)	2019-2023	231,664.71%
BioNexus Gene Lab Corp Common stock (BGLC)	2019-2023	129,168.29%
MicroCloud Hologram (HOLO)	2019-2023	20,476.39%
FitLife Brands, Inc Common Stock (FTLF)	2019-2023	19,000%
Weatherford International (WFRD)	2019-2023	18,301.57%
Applied Digital (APLD)	2019-2023	10,020.12%
Foremost Lithium Resource & Technology Ltd Common stock (FMST)	2019-2023	4,991.65%
Celsius (CELH)	2019-2023	4,724.78%
Atlas Lithium Corporation Common Stock (ATLX)	2019-2023	4,070.67%
Centrus Energy (LEU)	2019-2023	3,217.68%
Graf Industrial Corp Warrants (each warrant exercisable for one-half of one share of common stock each at an exercise price of $1150 per share) (GRAF.WT)	2019-2023	3,121.34%
JIN MEDICAL INTERNATIONAL LTD Ordinary Shares (ZJYL)	2019-2023	3,000.63%
Oxbridge Re Holdings Equity Warrant (OXBRW)	2019-2023	2,990.91%
Enphase Energy (ENPH)	2019-2023	2,754%
374Water Inc Common Stock (SCWO)	2019-2023	2,740%
Axsome Therapeutics (AXSM)	2019-2023	2,732.38%
Cassava Sciences (SAVA)	2019-2023	2,548.24%
Castellum (CTM)	2019-2023	1,998.59%
Super Micro Computer (SMCI)	2019-2023	1,961.35%
Sigma Lithium Resources (SGML)	2019-2023	1,931.57%
Aehr Test Systems (AEHR)	2019-2023	1,768.31%