Flexible Solutions International (FSI) had the highest return between 1999 and 2000 by a US stock, returning 11,168.6%.

ASSET	YEARS	% RETURN
Flexible Solutions International (FSI)	1999-2000	11,168.63%
Empire Petroleum (EP)	1999-2000	10,294.64%
OPTIMIZERx (OPRX)	1999-2000	1,600%
Myriad Genetics (MYGN)	1999-2000	1,554.98%
FuelCell Energy (FCEL)	1999-2000	1,409.61%
Laboratory Corporation of America (LH)	1999-2000	1,180.1%
Qualcomm (QCOM)	1999-2000	1,153.87%
Check Point Software Technologies (CHKP)	1999-2000	1,061.41%
Ciena (CIEN)	1999-2000	969.96%
Innodata (INOD)	1999-2000	945.63%
Suzano Papel e Celulose SA ADR (SUZ)	1999-2000	887.99%
Titan Pharmaceuticals (TTNP)	1999-2000	875.72%
Patterson-UTI Energy (PTEN)	1999-2000	803.03%
Biogen (BIIB)	1999-2000	705.57%
Quest Diagnostics (DGX)	1999-2000	700.01%
Algorhythm (RIME)	1999-2000	642.92%
BlackBerry (BB)	1999-2000	592.82%
Amtech Systems (ASYS)	1999-2000	540%
Forward Air (FWRD)	1999-2000	498.99%
Sono-Tek (SOTK)	1999-2000	476.92%
NetApp (NTAP)	1999-2000	440.53%
Regeneron Pharmaceuticals (REGN)	1999-2000	403.8%
SurModics (SRDX)	1999-2000	403.42%
Adobe Systems (ADBE)	1999-2000	399.31%
Infosys Ltd ADR (INFY)	1999-2000	398.99%