Check-Cap (CHEK) had the highest return in November 2025 by a US stock, returning 13,502.9%.

ASSET	MONTH	% RETURN
Check-Cap (CHEK)	November 2025	13,502.94%
Maywood Acquisition Corp Class A Ordinary Shares (MAYA)	November 2025	2,317.79%
WeShop Holdings Limited Class A Ordinary Shares (WSHP)	November 2025	602.8%
MMTEC (MTC)	November 2025	312.12%
SMX (Security Matters) Public Limited Company Class A Ordinary Shares (SMX)	November 2025	285.35%
Magnitude International Ltd Ordinary Shares (MAGH)	November 2025	261.81%
Cypherpunk Technologies (CYPH)	November 2025	244.59%
Olema Pharmaceuticals (OLMA)	November 2025	214.67%
NUVB-WT (NUVB.WT)	November 2025	189%
Mersana Therapeutics (MRSN)	November 2025	187.53%
PACS (PACS)	November 2025	175.89%
MaxsMaking Inc Class A Ordinary Shares (MAMK)	November 2025	173.68%
Alto Ingredients (ALTO)	November 2025	155%
Cogent Biosciences (COGT)	November 2025	147.51%
Galecto (GLTO)	November 2025	146.26%
Verrica Pharmaceuticals (VRCA)	November 2025	145.95%
Annovis Bio (ANVS)	November 2025	145.19%
Ridgetech (RDGT)	November 2025	143.71%
CCH Holdings Ltd Ordinary Shares (CCHH)	November 2025	120.25%
Quince Therapeutics (QNCX)	November 2025	119.88%
Evoke Pharma (EVOK)	November 2025	113.33%
Lake Superior Acquisition Corp Rights (LKSPR)	November 2025	105%
Forge Global (FRGE)	November 2025	104.14%
Cidara Therapeutics (CDTX)	November 2025	103.27%
Relmada Therapeutics (RLMD)	November 2025	103.15%