Sapiens International (SPNS) has had the highest return this month by a US stock, returning 32,102.2%.

ASSET	MONTH	% RETURN
Sapiens International (SPNS)	December 2025	32,102.22%
Capricor Therapeutics (CAPR)	December 2025	440.19%
NovaBay Pharmaceuticals (NBY)	December 2025	323.15%
Heartbeam (BEAT)	December 2025	312.65%
Aimei Health Technology Co, Ltd Ordinary Share (AFJK)	December 2025	292.95%
XTL Biopharmaceuticals Ltd ADR (XTLB)	December 2025	239.57%
Ascent Solar Technologies, Inc Common Stock (ASTI)	December 2025	208.54%
SMX (Security Matters) Public Limited Company Class A Ordinary Shares (SMX)	December 2025	191.28%
cbdMD (YCBD)	December 2025	171.69%
CapsoVision, Inc Common Stock (CV)	December 2025	147.6%
Climb Bio (CLYM)	December 2025	145.99%
Sable Offshore (SOC)	December 2025	144.92%
Sidus Space (SIDU)	December 2025	136.05%
Micromobility (MCOM)	December 2025	133.33%
JX Luxventure (JXG)	December 2025	130.76%
Wave Life Sciences (WVE)	December 2025	130%
Polyrizon Ltd Ordinary Shares (PLRZ)	December 2025	121.78%
Regencell Bioscience (RGC)	December 2025	119.37%
Hycroft Mining (HYMC)	December 2025	119.14%
FAST TRACK (FTRK)	December 2025	114.02%
Structure Therapeutics Inc American Depositary Shares (GPCR)	December 2025	102.18%
Evoke Pharma (EVOK)	December 2025	97.7%
Innovative Solutions and Support (ISSC)	December 2025	97.6%
PetMed Express (PETS)	December 2025	94.32%
Samfine Creation (SFHG)	December 2025	91.75%