Regencell Bioscience (RGC) has had the highest return this year by a US stock, returning 17,078.1%.

ASSET	YEAR	% RETURN
Regencell Bioscience (RGC)	2025	17,078.14%
Kindly (NAKAW)	2025	5,550%
DeFi Development (DFDV)	2025	2,817.22%
HCM II Acquisition (HONDW)	2025	1,882.76%
TMC the metals company Inc Warrants (TMCWW)	2025	1,258.49%
K Wave Media (KWMWW)	2025	1,236.89%
SRM Entertainment, Inc Common Stock (SRM)	2025	1,166.43%
M3-Brigade Acquisition V Corp Warrant (MBAVW)	2025	1,157.86%
Kindly (NAKA)	2025	1,134.68%
Kindly MD, Inc Common Stock (KDLY)	2025	1,134.68%
Diginex Limited Ordinary Shares (DGNX)	2025	992.96%
Asset Entities Inc Class B Common Stock (ASST)	2025	872%
Aeva Technologies, Inc Warrants (AEVAW)	2025	765.8%
mF International Limited Ordinary Shares (MFI)	2025	752.17%
Oncology Institute (TOI)	2025	667.97%
Oncology Institute (TOIIW)	2025	665.48%
Circle Internet (CRCL)	2025	618.23%
Columbus Circle Capital Corp I Warrant (CCCMW)	2025	616.67%
Quantum BioPharma (QNTM)	2025	613.95%
Dave Inc Warrants (DAVEW)	2025	599.63%
Webull Corporation Warrants (BULLW)	2025	593.79%
Protagenic Therapeutics (PTIXW)	2025	563.08%
GSR III Acquisition Corp Right (GSRTR)	2025	535.14%
Aeva Technologies, Inc Common Stock (AEVA)	2025	516.67%
Dominari (DOMH)	2025	515.91%