Aurora Innovation (AUR) had the lowest return in January 2022 by a mid-cap US stock, returning -57.6%.

ASSET	MONTH	% RETURN
Aurora Innovation (AUR)	January 2022	-57.57%
Fluence Energy (FLNC)	January 2022	-47.93%
Archer Aviation (ACHR)	January 2022	-47.5%
Alignment Healthcare LLC (ALHC)	January 2022	-46.33%
Kingsoft Cloud Holdings (KC)	January 2022	-45.48%
Eos Energy Enterprises (EOSE)	January 2022	-45.38%
Global-E Online (GLBE)	January 2022	-43.97%
Navitas Semiconductor (NVTS)	January 2022	-41.97%
Remitly Global (RELY)	January 2022	-41.83%
Purecycle Technologies (PCT)	January 2022	-39.75%
TG Therapeutics (TGTX)	January 2022	-39.52%
Rush Street Interactive (RSI)	January 2022	-38.92%
Adaptive Biotechnologies (ADPT)	January 2022	-37.98%
Dyne Therapeutics (DYN)	January 2022	-37.33%
Hycroft Mining (HYMC)	January 2022	-36.92%
Calix (CALX)	January 2022	-36.75%
Braze (BRZE)	January 2022	-36.09%
10X Genomics (TXG)	January 2022	-35.24%
Kymera Therapeutics (KYMR)	January 2022	-34.74%
Cipher Mining (CIFR)	January 2022	-34.2%
Olema Pharmaceuticals (OLMA)	January 2022	-33.54%
Monday (MNDY)	January 2022	-33.3%
Opendoor Technologies (OPEN)	January 2022	-33.13%
Disc Medicine (IRON)	January 2022	-33.11%
Crinetics Pharmaceuticals (CRNX)	January 2022	-32.58%

Mid-cap stocks are treated as having a market cap between $2B and $10B.