Vertex Pharmaceuticals (VRTX) had the lowest return in March 2006 by a US stock in the S&P 500 (GSPC), returning -15.6%.

ASSET	MONTH	% RETURN
Vertex Pharmaceuticals (VRTX)	March 2006	-15.56%
Advanced Micro Devices (AMD)	March 2006	-14.97%
Western Digital (WDC)	March 2006	-13.84%
Mosaic (MOS)	March 2006	-9.8%
JB Hunt Transport Services (JBHT)	March 2006	-9.5%
Adobe Systems (ADBE)	March 2006	-9.27%
Apple (AAPL)	March 2006	-8.89%
Franklin Resources (BEN)	March 2006	-8.56%
MarketAxess (MKTX)	March 2006	-8.52%
Capital One Financial (COF)	March 2006	-8.4%
Carnival (CCL)	March 2006	-8.27%
CenterPoint Energy (CNP)	March 2006	-8.23%
Accenture (ACN)	March 2006	-8.21%
Dominion Energy (D)	March 2006	-8.03%
Teradyne (TER)	March 2006	-7.9%
CMS Energy (CMS)	March 2006	-7.83%
Interpublic Group of Companies (IPG)	March 2006	-7.72%
KLA-Tencor (KLAC)	March 2006	-7.53%
American Electric Power (AEP)	March 2006	-7.18%
Fair Isaac (FICO)	March 2006	-7.15%
Exelon (EXC)	March 2006	-7.11%
Edison International (EIX)	March 2006	-6.91%
Lennox International (LII)	March 2006	-6.83%
PPL (PPL)	March 2006	-6.76%
Public Service Enterprise (PEG)	March 2006	-6.69%