Commerce Bancshares (CBSH) had the lowest return between 1975 and 1981 by a US stock, returning -100%.

ASSET	YEARS	% RETURN
Commerce Bancshares (CBSH)	1975-1981	-100%
Helmerich and Payne (HP)	1975-1981	-100%
US Energy (USEG)	1975-1981	-86.09%
Brunswick (BC)	1975-1981	-81.92%
Terex (TEX)	1975-1981	-73.69%
Molson Coors Brewing (TAP)	1975-1981	-65.98%
Biomerica (BMRA)	1975-1981	-55.56%
Electro-Sensors (ELSE)	1975-1981	-46.43%
Kinross Gold (KGC)	1975-1981	-44.84%
Schlumberger (SLB)	1975-1981	-44.13%
Bio-Rad Laboratories (BIO)	1975-1981	-43.27%
Agnico Eagle Mines (AEM)	1975-1981	-41.89%
Tenet Healthcare (THC)	1975-1981	-34.43%
Commercial Metals (CMC)	1975-1981	-34.06%
Citizens (CIA)	1975-1981	-29.63%
Bridgford Foods (BRID)	1975-1981	-28.52%
Colgate-Palmolive (CL)	1975-1981	-27.95%
Weatherford International (WFRD)	1975-1981	-25.63%
Educational Development (EDUC)	1975-1981	-25.03%
NiSource (NI)	1975-1981	-24.79%
Chicago Rivet & Machine (CVR)	1975-1981	-24.32%
Target (TGT)	1975-1981	-24.05%
Apple (AAPL)	1975-1981	-23.02%
Servotronics (SVT)	1975-1981	-20.67%
SIFCO Industries (SIF)	1975-1981	-20.47%