Fubotv (FUBO) had the lowest return between 2010 and 2019 by a US stock with a market cap of $300M+, returning -100%.

ASSET	YEARS	% RETURN
Fubotv (FUBO)	2010-2019	-100%
MetroCity Bankshares (MCBS)	2010-2019	-100%
Gevo (GEVO)	2010-2019	-100%
Ocugen (OCGN)	2010-2019	-99.92%
Red Cat (RCAT)	2010-2019	-99.85%
Capricor Therapeutics (CAPR)	2010-2019	-99.78%
Oruka Therapeutics (ORKA)	2010-2019	-99.77%
Riot Blockchain (RIOT)	2010-2019	-99.72%
Altimmune (ALT)	2010-2019	-99.71%
Viridian Therapeutics (VRDN)	2010-2019	-99.65%
Gyre Therapeutics (GYRE)	2010-2019	-99.59%
FuelCell Energy (FCEL)	2010-2019	-99.54%
Delcath Systems (DCTH)	2010-2019	-99.42%
Centrus Energy (LEU)	2010-2019	-99.35%
Savara (SVRA)	2010-2019	-99.34%
Mercurity Fintech Holding Inc ADR (MFH)	2010-2019	-99.26%
Platinum Group Metals (PLG)	2010-2019	-99.18%
Obsidian Energy (OBE)	2010-2019	-99.13%
Lightbridge (LTBR)	2010-2019	-98.82%
Civitas Resources (CIVI)	2010-2019	-98.65%
Tidewater (TDW)	2010-2019	-98.5%
Quantum Computing (QUBT)	2010-2019	-98.42%
American Superconductor (AMSC)	2010-2019	-98.11%
Euroseas (ESEA)	2010-2019	-98.02%
Benitec Biopharma Ltd ADR (BNTC)	2010-2019	-97.68%