Akero Therapeutics (AKRO) had the lowest return in October 2023 by a mid-cap US stock, returning -76.6%.

ASSET	MONTH	% RETURN
Akero Therapeutics (AKRO)	October 2023	-76.55%
Bitdeer Technologies Group Class A Ordinary Shares (BTDR)	October 2023	-61.99%
Arcutis Biotherapeutics (ARQT)	October 2023	-57.22%
CommScope (COMM)	October 2023	-56.34%
VinFast Auto Ltd Ordinary Shares (VFS)	October 2023	-51.13%
GeneDx (WGS)	October 2023	-47.75%
Semtech (SMTC)	October 2023	-45.68%
Sarepta Therapeutics (SRPT)	October 2023	-44.09%
Praxis Precision Medicines (PRAX)	October 2023	-42.13%
Establishment Labs (ESTA)	October 2023	-40.33%
Ondas (ONDS)	October 2023	-37.97%
Vicor (VICR)	October 2023	-34.27%
Enphase Energy (ENPH)	October 2023	-33.24%
Quantum Computing (QUBT)	October 2023	-32.69%
Applied Opt (AAOI)	October 2023	-32.45%
Sezzle (SEZL)	October 2023	-31.92%
Recursion Pharmaceuticals (RXRX)	October 2023	-31.07%
Nuscale Power (SMR)	October 2023	-31.02%
Compass (COMP)	October 2023	-31.01%
Chart Industries (GTLS)	October 2023	-30.95%
TransMedics (TMDX)	October 2023	-30.87%
Grupo Aeroportuario del Centro Norte SAB de CV (OMAB)	October 2023	-29.98%
Alphatec (ATEC)	October 2023	-29.22%
Perimeter Solutions (PRM)	October 2023	-28.89%
Nuvation Bio (NUVB)	October 2023	-28.06%

Mid-cap stocks are treated as having a market cap between $2B and $10B.