Applied Digital (APLD) had the lowest return in January 2022 by a mid-cap US stock or mid-cap US stock, returning -64.2%.

ASSET	MONTH	% RETURN
Applied Digital (APLD)	January 2022	-64.2%
89bio (ETNB)	January 2022	-55.07%
Fluence Energy (FLNC)	January 2022	-47.93%
Archer Aviation (ACHR)	January 2022	-47.5%
Alignment Healthcare LLC (ALHC)	January 2022	-46.33%
Kingsoft Cloud Holdings (KC)	January 2022	-45.48%
Eos Energy Enterprises (EOSE)	January 2022	-45.38%
PureCycle Technologies (PCTTW)	January 2022	-44.72%
Global-E Online (GLBE)	January 2022	-43.97%
Enovix (ENVX)	January 2022	-42.75%
BridgeBio Pharma (BBIO)	January 2022	-42.44%
Remitly Global (RELY)	January 2022	-41.83%
Purecycle Technologies (PCT)	January 2022	-39.75%
TG Therapeutics (TGTX)	January 2022	-39.52%
Rush Street Interactive (RSI)	January 2022	-38.92%
Calix (CALX)	January 2022	-36.75%
Braze (BRZE)	January 2022	-36.09%
Kymera Therapeutics (KYMR)	January 2022	-34.74%
Sharplink Gaming (SBET)	January 2022	-34.7%
Cipher Mining (CIFR)	January 2022	-34.2%
Opendoor Technologies (OPEN)	January 2022	-33.13%
Disc Medicine (IRON)	January 2022	-33.11%
Madrigal Pharmaceuticals (MDGL)	January 2022	-32.93%
Crinetics Pharmaceuticals (CRNX)	January 2022	-32.58%
Trex (TREX)	January 2022	-32.5%

Mid-cap stocks are treated as having a market cap between $2B and $10B.