8/25/25 through 12/31/25 best mid cap stock

Praxis Precision Medicines  (PRAX) had the highest return between August 25, 2025 and December 31, 2025 by a mid-cap US stock, returning 511.2%.

ASSETDATE% RETURN
Praxis Precision Medicines  (PRAX)
8/25/2025 - 12/31/2025
511.24%
AXT (AXTI)
8/25/2025 - 12/31/2025
483.93%
PACS (PACS)
8/25/2025 - 12/31/2025
218.59%
Arrowhead Pharmaceuticals (ARWR)
8/25/2025 - 12/31/2025
209.94%
Planet Labs PBC (PL)
8/25/2025 - 12/31/2025
190.86%
Nova Minerals (NVA)
8/25/2025 - 12/31/2025
185.28%
Cogent Biosciences (COGT)
8/25/2025 - 12/31/2025
184.84%
Kodiak Sciences (KOD)
8/25/2025 - 12/31/2025
172.78%
GRAIL, LLC (GRAL)
8/25/2025 - 12/31/2025
151.74%
Butterfly Network (BFLY)
8/25/2025 - 12/31/2025
148.37%
Belite Bio Inc ADR (BLTE)
8/25/2025 - 12/31/2025
146.85%
ChronoScale (CHRN)
8/25/2025 - 12/31/2025
142.7%
Erasca (ERAS)
8/25/2025 - 12/31/2025
135.44%
Cipher Mining (CIFR)
8/25/2025 - 12/31/2025
133.77%
Axogen (AXGN)
8/25/2025 - 12/31/2025
129.68%
Relay Therapeutics  (RLAY)
8/25/2025 - 12/31/2025
129.27%
Arcus Biosciences (RCUS)
8/25/2025 - 12/31/2025
126.09%
Sphere Entertainment (SPHR)
8/25/2025 - 12/31/2025
123.82%
MBX Biosciences, Inc Common Stock (MBX)
8/25/2025 - 12/31/2025
121.18%
American Eagle Outfitters (AEO)
8/25/2025 - 12/31/2025
116.17%
Almonty Industries Inc Common Shares (ALM)
8/25/2025 - 12/31/2025
115.93%
Travere Therapeutics (TVTX)
8/25/2025 - 12/31/2025
113.34%
Ondas (ONDS)
8/25/2025 - 12/31/2025
108.55%
Immunome  (IMNM)
8/25/2025 - 12/31/2025
108.54%
BitVentures (BVC)
8/25/2025 - 12/31/2025
103.57%
Mid-cap stocks are treated as having a market cap between $2B and $10B.