
Praxis Precision Medicines (PRAX) had the highest return between August 25, 2025 and December 31, 2025 by a mid-cap US stock, returning 511.2%.
| ASSET | DATE | % RETURN |
|---|---|---|
Praxis Precision Medicines (PRAX) | 8/25/2025 - 12/31/2025 | 511.24% |
AXT (AXTI) | 8/25/2025 - 12/31/2025 | 483.93% |
PACS (PACS) | 8/25/2025 - 12/31/2025 | 218.59% |
Arrowhead Pharmaceuticals (ARWR) | 8/25/2025 - 12/31/2025 | 209.94% |
Planet Labs PBC (PL) | 8/25/2025 - 12/31/2025 | 190.86% |
Nova Minerals (NVA) | 8/25/2025 - 12/31/2025 | 185.28% |
Cogent Biosciences (COGT) | 8/25/2025 - 12/31/2025 | 184.84% |
Kodiak Sciences (KOD) | 8/25/2025 - 12/31/2025 | 172.78% |
GRAIL, LLC (GRAL) | 8/25/2025 - 12/31/2025 | 151.74% |
Butterfly Network (BFLY) | 8/25/2025 - 12/31/2025 | 148.37% |
Belite Bio Inc ADR (BLTE) | 8/25/2025 - 12/31/2025 | 146.85% |
ChronoScale (CHRN) | 8/25/2025 - 12/31/2025 | 142.7% |
Erasca (ERAS) | 8/25/2025 - 12/31/2025 | 135.44% |
Cipher Mining (CIFR) | 8/25/2025 - 12/31/2025 | 133.77% |
Axogen (AXGN) | 8/25/2025 - 12/31/2025 | 129.68% |
Relay Therapeutics (RLAY) | 8/25/2025 - 12/31/2025 | 129.27% |
Arcus Biosciences (RCUS) | 8/25/2025 - 12/31/2025 | 126.09% |
Sphere Entertainment (SPHR) | 8/25/2025 - 12/31/2025 | 123.82% |
MBX Biosciences, Inc Common Stock (MBX) | 8/25/2025 - 12/31/2025 | 121.18% |
American Eagle Outfitters (AEO) | 8/25/2025 - 12/31/2025 | 116.17% |
Almonty Industries Inc Common Shares (ALM) | 8/25/2025 - 12/31/2025 | 115.93% |
Travere Therapeutics (TVTX) | 8/25/2025 - 12/31/2025 | 113.34% |
Ondas (ONDS) | 8/25/2025 - 12/31/2025 | 108.55% |
Immunome (IMNM) | 8/25/2025 - 12/31/2025 | 108.54% |
BitVentures (BVC) | 8/25/2025 - 12/31/2025 | 103.57% |
Mid-cap stocks are treated as having a market cap between $2B and $10B.