QXO (QXO) had the highest return in June 2010 by a large-cap US stock, returning 125%.

ASSET	MONTH	% RETURN
QXO (QXO)	June 2010	125%
Neurocrine Biosciences (NBIX)	June 2010	40.7%
Tesla (TSLA)	June 2010	25.42%
Genmab A-S (GMAB)	June 2010	21.95%
Leonardo DRS, Inc Common Stock (DRS)	June 2010	15.79%
Berkshire Hathaway (BRK.A)	June 2010	13.86%
Berkshire Hathaway (BRK.B)	June 2010	13.76%
Newmont Goldcorp (NEM)	June 2010	13.51%
Stellantis (STLA)	June 2010	11.88%
DexCom (DXCM)	June 2010	11.8%
Edwards Lifesciences (EW)	June 2010	11.55%
AstraZeneca PLC ADR (AZN)	June 2010	11.37%
Baker Hughes (BKR)	June 2010	11%
Companhia de Saneamento Basico do Estado de Sao Paulo SABESP ADR (SBS)	June 2010	10.74%
Centrais Elétricas Brasileiras SA - Eletrobrás (EBR.B)	June 2010	10.39%
Energy Transfer (ET)	June 2010	10.33%
J M Smucker (SJM)	June 2010	9.87%
Telefonaktiebolaget LM Ericsson B ADR (ERIC)	June 2010	9.43%
Bristol-Myers Squibb (BMY)	June 2010	9.3%
Centrais Electricas Brasileiras (EBR)	June 2010	8.97%
Banco Santander Chile (BSAC)	June 2010	8.58%
Ball (BALL)	June 2010	8.53%
Pegasystems (PEGA)	June 2010	8.45%
Cooper Companies (COO)	June 2010	8.39%
HDFC Bank Limited ADR (HDB)	June 2010	7.91%

Large-cap stocks are treated as having a market cap of $10B+.