Ferguson (FERG) had the highest return between 2009 and 2010 by a large-cap US stock, returning 484,754.8%.

ASSET	YEARS	% RETURN
Ferguson (FERG)	2009-2010	484,754.76%
Teck Resources Ltd Class B (TECK)	2009-2010	1,162.83%
Pilgrims Pride (PPC)	2009-2010	958.3%
Lululemon Athletica (LULU)	2009-2010	760.63%
Las Vegas Sands (LVS)	2009-2010	678.82%
Baidu (BIDU)	2009-2010	631.29%
Ford Motor (F)	2009-2010	630.06%
Cheniere Energy Partners (CQP)	2009-2010	616.27%
Primo Brands (PRMB)	2009-2010	534.49%
Wheaton Precious Metals (WPM)	2009-2010	510%
Netflix (NFLX)	2009-2010	495.2%
Somnigroup International (SGI)	2009-2010	480.59%
F5 Networks (FFIV)	2009-2010	469.63%
Tenet Healthcare (THC)	2009-2010	466.95%
Booking (BKNG)	2009-2010	437.97%
Skyworks Solutions (SWKS)	2009-2010	415.85%
DexCom (DXCM)	2009-2010	394.57%
Freeport-McMoran Copper & Gold (FCX)	2009-2010	392.64%
AerCap (AER)	2009-2010	382.57%
Williams-Sonoma (WSM)	2009-2010	379.66%
CBRE Group Inc Class A (CBRE)	2009-2010	362.3%
Smurfit WestRock (SW)	2009-2010	356.02%
Incyte (INCY)	2009-2010	335.79%
Cummins (CMI)	2009-2010	323.71%
KKR (KKR)	2009-2010	318.02%

Large-cap stocks are treated as having a market cap of $10B+.