best large-cap stocks 2000 to 2021

InterContinental Hotels Group PLC ADR (IHG) had the highest return between 2000 and 2021 by a large-cap US stock, returning 59,224,100%.

ASSETYEARS% RETURN
InterContinental Hotels Group PLC ADR (IHG)
2000-2021
59,224,100%
QXO (QXO)
2000-2021
14,150,850%
Monster Beverage (MNST)
2000-2021
107,568.16%
Netflix (NFLX)
2000-2021
52,014.19%
Deckers Outdoor (DECK)
2000-2021
41,773.59%
Old Dominion Freight Line (ODFL)
2000-2021
38,693.52%
NVIDIA (NVDA)
2000-2021
32,439.56%
Tesla (TSLA)
2000-2021
27,709.27%
Tractor Supply (TSCO)
2000-2021
26,964.43%
Apple (AAPL)
2000-2021
22,018.01%
Texas Pacific Land (TPL)
2000-2021
20,604.3%
Intuitive Surgical (ISRG)
2000-2021
17,865.9%
IDEXX Laboratories (IDXX)
2000-2021
16,329.46%
Clean Harbors (CLH)
2000-2021
16,271.84%
NetEase (NTES)
2000-2021
15,438.82%
NVR (NVR)
2000-2021
12,274.6%
Waste Connections (WCN)
2000-2021
11,794.34%
Edwards Lifesciences (EW)
2000-2021
10,094.37%
Mastercard (MA)
2000-2021
9,484.45%
UnitedHealth (UNH)
2000-2021
9,013.97%
Tyler Technologies (TYL)
2000-2021
8,865.83%
Domino's Pizza Inc Common Stock (DPZ)
2000-2021
8,444.25%
West Pharmaceutical Services (WST)
2000-2021
8,320.72%
Manhattan Associates (MANH)
2000-2021
7,957.73%
BlackRock (BLK)
2000-2021
7,863.83%
Large-cap stocks are treated as having a market cap of $10B+.