Ferguson (FERG) had the highest return between 2006 and 2011 by a large-cap US stock, returning 66,420.3%.

ASSET	YEARS	% RETURN
Ferguson (FERG)	2006-2011	66,420.33%
Booking (BKNG)	2006-2011	1,995.47%
Baidu (BIDU)	2006-2011	1,712.76%
CF Industries (CF)	2006-2011	876.3%
Mastercard (MA)	2006-2011	840.61%
Ambev SA ADR (ABEV)	2006-2011	759.9%
Deckers Outdoor (DECK)	2006-2011	695.74%
Chipotle Mexican Grill (CMG)	2006-2011	650.53%
Credicorp (BAP)	2006-2011	465.45%
Apple (AAPL)	2006-2011	459.54%
Dollar Tree (DLTR)	2006-2011	420.03%
TechnipFMC (FTI)	2006-2011	407.09%
Sociedad Quimica y Minera de Chile SA ADR B (SQM)	2006-2011	396.38%
Wheaton Precious Metals (WPM)	2006-2011	386.86%
Transdigm (TDG)	2006-2011	372.23%
Somnigroup International (SGI)	2006-2011	371.01%
Monster Beverage (MNST)	2006-2011	357.61%
XPO Logistics (XPO)	2006-2011	347.43%
Novo Nordisk A-S (NVO)	2006-2011	347.21%
Clean Harbors (CLH)	2006-2011	343.49%
Illumina (ILMN)	2006-2011	327.79%
Companhia de Saneamento Basico do Estado de Sao Paulo SABESP ADR (SBS)	2006-2011	324.51%
Cummins (CMI)	2006-2011	322.75%
Southern Copper (SCCO)	2006-2011	300.54%
Intuitive Surgical (ISRG)	2006-2011	289.44%

Large-cap stocks are treated as having a market cap of $10B+.