Monster Beverage (MNST) had the highest return between 2004 and 2005 by a large-cap US stock in the S&P 500 (GSPC), returning 1,772.2%.

ASSET	YEARS	% RETURN
Monster Beverage (MNST)	2004-2005	1,772.18%
Intuitive Surgical (ISRG)	2004-2005	585.79%
Apple (AAPL)	2004-2005	567.35%
CME (CME)	2004-2005	414.46%
Valero Energy (VLO)	2004-2005	345.32%
Hologic (HOLX)	2004-2005	333.62%
Alphabet Inc Class A (GOOGL)	2004-2005	314.82%
Nasdaq (NDAQ)	2004-2005	290.89%
Autodesk (ADSK)	2004-2005	253.78%
EOG Resources (EOG)	2004-2005	220.96%
CBRE Group Inc Class A (CBRE)	2004-2005	209.73%
Williams Companies (WMB)	2004-2005	205.97%
Texas Pacific Land Trust (TPL)	2004-2005	190.58%
Vertex Pharmaceuticals (VRTX)	2004-2005	167.34%
Nucor (NUE)	2004-2005	147.43%
Halliburton (HAL)	2004-2005	144.25%
Humana (HUM)	2004-2005	135.7%
Contura Energy (CTRA)	2004-2005	132.41%
L3Harris Technologies (LHX)	2004-2005	131%
F5 Networks (FFIV)	2004-2005	127.4%
Devon Energy (DVN)	2004-2005	121.45%
Cognizant Technology Solutions Corp Class A (CTSH)	2004-2005	117.71%
NRG Energy (NRG)	2004-2005	114.18%
Salesforce (CRM)	2004-2005	113.67%
Edison International (EIX)	2004-2005	112.57%

Large-cap stocks are treated as having a market cap of $10B+.