Future Fintech (FTFT) had the highest return in the 2000s by a US stock, returning 52,735,900%.

ASSET	DECADE	% RETURN
Future Fintech (FTFT)	2000s	52,735,900%
Eldorado Gold (EGO)	2000s	22,572,433.33%
Zivo Bioscience (ZIVO)	2000s	13,090,809.09%
InterContinental Hotels Group PLC ADR (IHG)	2000s	9,733,500%
Ridgetech (RDGT)	2000s	6,872,627.27%
Cemtrex (CETX)	2000s	4,938,903.31%
NovaBay Pharmaceuticals (NBY)	2000s	3,424,939.16%
India Globalization Capital (IGC)	2000s	2,299,900%
Taoping (TAOP)	2000s	1,478,398.57%
Hirequest (HQI)	2000s	924,250%
Viewbix Inc Common Stock (VBIX)	2000s	794,734.01%
Live Ventures (LIVE)	2000s	356,364.06%
NextTrip (NTRP)	2000s	159,900%
Ring Energy (REI)	2000s	133,233.33%
Inseego (INSG)	2000s	132,733.33%
ProMIS Neurosciences (PMN)	2000s	77,002.8%
Danaos (DAC)	2000s	68,818.66%
Hudbay Minerals (HBM)	2000s	64,490.22%
Xcel Brands (XELB)	2000s	57,160%
DeFi Technologies (DEFT)	2000s	42,500%
Perspective Therapeutics (CATX)	2000s	29,563.33%
Marker Therapeutics (MRKR)	2000s	25,656.1%
Astrana Health (ASTH)	2000s	21,112.12%
ImmunoPrecise Antibodies (HYFT)	2000s	20,471.43%
Ovintiv (OVV)	2000s	19,668.99%