InterContinental Hotels Group PLC ADR (IHG) had the highest return between 2002 and 2009 by a US stock with a market cap of $10B+, returning 9,928,700%.

ASSET	YEARS	% RETURN
InterContinental Hotels Group PLC ADR (IHG)	2002-2009	9,928,700%
National Grid PLC ADR (NGG)	2002-2009	1,410,385.71%
Natwest (NWG)	2002-2009	590,100%
NetEase (NTES)	2002-2009	19,976.61%
Monster Beverage (MNST)	2002-2009	7,139.82%
Grupo Cibest (CIB)	2002-2009	3,923.13%
Banco Bradesco SA ADR (BBD)	2002-2009	3,668.55%
ArcelorMittal SA ADR (MT)	2002-2009	2,869.99%
Southern Copper (SCCO)	2002-2009	2,644.83%
Deckers Outdoor (DECK)	2002-2009	2,200.94%
Vale SA ADR (VALE)	2002-2009	2,194.21%
Apple (AAPL)	2002-2009	1,810.66%
Clean Harbors (CLH)	2002-2009	1,679.4%
Sociedad Quimica y Minera de Chile SA ADR B (SQM)	2002-2009	1,521.38%
Tenaris SA ADR (TS)	2002-2009	1,470.66%
Intuitive Surgical (ISRG)	2002-2009	1,448.02%
Alamos Gold (AGI)	2002-2009	1,434.69%
Ambev SA ADR (ABEV)	2002-2009	1,289.55%
Chunghwa Telecom (CHT)	2002-2009	1,286.52%
Cognizant Technology Solutions Corp Class A (CTSH)	2002-2009	1,229.49%
Petroleo Brasileiro Petrobras SA ADR (PBR)	2002-2009	1,226.54%
Petróleo Brasileiro SA - Petrobras (PBR.A)	2002-2009	1,209.49%
Canadian Natural Resources (CNQ)	2002-2009	1,184.61%
Amazon (AMZN)	2002-2009	1,130.07%
Trip Group Ltd ADR (TCOM)	2002-2009	1,118.93%