best performing stocks with a $5b+ market cap from june 2022 to now

QMMM Holdings Limited Ordinary Shares (QMMM) has had the highest return between June 1, 2022 and September 25, 2025 by a US stock with a market cap of $5B+, returning 3,066.7%.

ASSET DATE % RETURN
QMMM Holdings Limited Ordinary Shares (QMMM)
6/1/2022 - 9/25/2025
3,066.67%
Rhythm Pharmaceuticals (RYTM)
6/1/2022 - 9/25/2025
2,684.77%
Verona Pharma PLC ADR (VRNA)
6/1/2022 - 9/25/2025
2,248.57%
Celestica (CLS)
6/1/2022 - 9/25/2025
2,068.26%
Palantir Technologies Inc Class A Common Stock (PLTR)
6/1/2022 - 9/25/2025
1,959.17%
Regencell Bioscience (RGC)
6/1/2022 - 9/25/2025
1,766.12%
Applovin (APP)
6/1/2022 - 9/25/2025
1,564.73%
Summit Therapeutics (SMMT)
6/1/2022 - 9/25/2025
1,385.51%
Credo Technology (CRDO)
6/1/2022 - 9/25/2025
1,360.22%
Sterling Construction (STRL)
6/1/2022 - 9/25/2025
1,285.06%
Oklo (OKLO)
6/1/2022 - 9/25/2025
1,259.27%
Hims Hers Health (HIMS)
6/1/2022 - 9/25/2025
1,221.34%
Vertiv (VRT)
6/1/2022 - 9/25/2025
1,201.52%
IONQ (IONQ)
6/1/2022 - 9/25/2025
1,186.76%
Robinhood Markets (HOOD)
6/1/2022 - 9/25/2025
1,173.09%
Carvana (CVNA)
6/1/2022 - 9/25/2025
1,172.27%
IES (IESC)
6/1/2022 - 9/25/2025
1,139.48%
MicroStrategy (MSTR)
6/1/2022 - 9/25/2025
1,137.08%
Modine Manufacturing (MOD)
6/1/2022 - 9/25/2025
1,083.25%
Fortress Transp & Infra Inv (FTAI)
6/1/2022 - 9/25/2025
1,047.33%
Centrus Energy (LEU)
6/1/2022 - 9/25/2025
961.54%
Rocket Lab USA (RKLB)
6/1/2022 - 9/25/2025
929.39%
NVIDIA (NVDA)
6/1/2022 - 9/25/2025
846.7%
Super Micro Computer (SMCI)
6/1/2022 - 9/25/2025
813.4%
Nuvalent (NUVL)
6/1/2022 - 9/25/2025
793.71%