BioNexus Gene Lab Corp Common stock (BGLC) had the highest return between 2020 and 2021 by a US stock, returning 6,234,046.3%.

ASSET	YEARS	% RETURN
BioNexus Gene Lab Corp Common stock (BGLC)	2020-2021	6,234,046.34%
MDxHealth SA ADR (MDXH)	2020-2021	865,354.55%
MicroCloud Hologram (HOLO)	2020-2021	577,362.44%
Integra Resources (ITRG)	2020-2021	358,233.33%
CareMax (CMAX)	2020-2021	69,718.18%
Applied Digital (APLD)	2020-2021	58,094.44%
Firefly Neuroscience (AIFF)	2020-2021	3,707.69%
Nuvve (NVVEW)	2020-2021	3,583.33%
HIVE Blockchain Technologies (HIVE)	2020-2021	3,541.38%
Novavax (NVAX)	2020-2021	3,485.71%
American Battery Technology Company Common Stock (ABAT)	2020-2021	3,243.75%
374Water Inc Common Stock (SCWO)	2020-2021	3,066.67%
Graf Industrial Corp Warrants (each warrant exercisable for one-half of one share of common stock each at an exercise price of $1150 per share) (GRAF.WT)	2020-2021	2,944.83%
Ascent Solar Technologies, Inc Common Stock (ASTI)	2020-2021	2,400%
GameStop (GME)	2020-2021	2,316.78%
Trump Media & Technology (DJTWW)	2020-2021	2,299.56%
Iqstel (IQST)	2020-2021	2,088.82%
Lightwave Logic (LWLG)	2020-2021	2,025.71%
CPI Card (PMTS)	2020-2021	1,961.11%
Empire Petroleum (EP)	2020-2021	1,911.51%
Riot Blockchain (RIOT)	2020-2021	1,858.77%
Zivo Bioscience (ZIVO)	2020-2021	1,639.39%
Guardforce AI (GFAI)	2020-2021	1,628%
Celldex Therapeutics (CLDX)	2020-2021	1,625%
Soluna (SLNH)	2020-2021	1,503.58%