Allarity Therapeutics (ALLR) had the lowest return between 2021 and 2023 by a US stock in the Nasdaq Composite (IXIC), returning -100%.

ASSET	YEARS	% RETURN
Allarity Therapeutics (ALLR)	2021-2023	-99.98%
Faraday Future Intelligent Electric (FFIE)	2021-2023	-99.97%
Oceanpal (OP)	2021-2023	-99.97%
Ensysce Biosciences (ENSC)	2021-2023	-99.96%
Infobird (IFBD)	2021-2023	-99.96%
Fangdd Network (DUO)	2021-2023	-99.96%
Ascent Solar Technologies, Inc Common Stock (ASTI)	2021-2023	-99.96%
Agrify (AGFY)	2021-2023	-99.95%
Connexa Sports Technologies (YYAI)	2021-2023	-99.94%
E-Home Household Service (EJH)	2021-2023	-99.93%
Greenlane (GNLN)	2021-2023	-99.93%
Siyata Mobile (SYTA)	2021-2023	-99.92%
Jaguar Animal Health (JAGX)	2021-2023	-99.92%
Nuwellis (NUWE)	2021-2023	-99.92%
Biodexa Pharmaceticals (BDRX)	2021-2023	-99.91%
Bone Biologics (BBLG)	2021-2023	-99.9%
Jiuzi (JZXN)	2021-2023	-99.9%
Versus Systems Inc. (VS)	2021-2023	-99.9%
Ontrak (OTRK)	2021-2023	-99.89%
Avalo Therapeutics (AVTX)	2021-2023	-99.88%
Transcode Therapeutics (RNAZ)	2021-2023	-99.86%
XTI Aerospace (XTIA)	2021-2023	-99.86%
Revelation Biosciences (REVB)	2021-2023	-99.86%
Akanda (AKAN)	2021-2023	-99.85%
American Rebel (AREB)	2021-2023	-99.85%