Answered April 18th, 2019

Nolan Ryan ties the MLB record for strikeouts in a nine-inning game with 19 in a win against Boston. It was his second of three 19-strikeout games in the 1974 season.

What are the most strikeouts in a game by Nolan Ryan?
Interpreted as:
What are the most strikeouts in a regular season game by Nolan Ryan?