Peyton Manning throws his 51st TD, breaking Tom Brady's 2007 single-season record. He finished 2013 with 55 TDs.
| NAME | SEASON | TM | GP | TD | CMP | ATT | PCT | YDS | AVG | YDS/G | TD% | INT | INT% | SCK | SCKY | RATE | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Peyton Manning | 2013 |  DEN | 16 | 55 | 450 | 659 | 68.3 | 5,477 | 8.3 | 342.3 | 8.3 | 10 | 1.5 | 18 | 120 | 115.1 |
| 2 |  | Patrick Mahomes | 2018 |  KC | 16 | 50 | 383 | 580 | 66.0 | 5,097 | 8.8 | 318.6 | 8.6 | 12 | 2.1 | 26 | 171 | 113.8 |
| 3 |  | Tom Brady | 2007 |  NE | 16 | 50 | 398 | 578 | 68.9 | 4,806 | 8.3 | 300.4 | 8.7 | 8 | 1.4 | 21 | 128 | 117.2 |
| 4 |  | Peyton Manning | 2004 |  IND | 16 | 49 | 336 | 497 | 67.6 | 4,557 | 9.2 | 284.8 | 9.9 | 10 | 2.0 | 13 | 101 | 121.1 |
| 5 |  | Dan Marino | 1984 |  MIA | 16 | 48 | 362 | 564 | 64.2 | 5,084 | 9.0 | 317.8 | 8.5 | 17 | 3.0 | 13 | 120 | 108.9 |
| 6 |  | Drew Brees | 2011 |  NO | 16 | 46 | 468 | 657 | 71.2 | 5,476 | 8.3 | 342.3 | 7.0 | 14 | 2.1 | 24 | 158 | 110.6 |
| 7 |  | Aaron Rodgers | 2011 |  GB | 15 | 45 | 343 | 502 | 68.3 | 4,643 | 9.2 | 309.5 | 9.0 | 6 | 1.2 | 36 | 219 | 122.5 |
| 8 | | Dan Marino | 1986 | MIA | 16 | 44 | 378 | 623 | 60.7 | 4,746 | 7.6 | 296.6 | 7.1 | 23 | 3.7 | 17 | 119 | 92.5 |
| 9 | | Drew Brees | 2012 | NO | 16 | 43 | 422 | 670 | 63.0 | 5,177 | 7.7 | 323.6 | 6.4 | 19 | 2.8 | 26 | 190 | 96.3 |
| 10 |  | Matthew Stafford | 2011 |  DET | 16 | 41 | 421 | 663 | 63.5 | 5,038 | 7.6 | 314.9 | 6.2 | 16 | 2.4 | 36 | 257 | 97.2 |
| 11 |  | Kurt Warner | 1999 |  STL | 16 | 41 | 325 | 499 | 65.1 | 4,353 | 8.7 | 272.1 | 8.2 | 13 | 2.6 | 29 | 201 | 109.2 |
| 12 | | Aaron Rodgers | 2016 | GB | 16 | 40 | 401 | 610 | 65.7 | 4,428 | 7.3 | 276.8 | 6.6 | 7 | 1.1 | 35 | 246 | 104.2 |
| 13 |  | Andrew Luck | 2014 | IND | 16 | 40 | 380 | 616 | 61.7 | 4,761 | 7.7 | 297.6 | 6.5 | 16 | 2.6 | 27 | 161 | 96.5 |
| 14 | | Andrew Luck | 2018 | IND | 16 | 39 | 430 | 639 | 67.3 | 4,593 | 7.2 | 287.1 | 6.1 | 15 | 2.3 | 18 | 134 | 98.7 |
| 15 | | Peyton Manning | 2014 | DEN | 16 | 39 | 395 | 597 | 66.2 | 4,727 | 7.9 | 295.4 | 6.5 | 15 | 2.5 | 17 | 118 | 101.5 |
| 16 | | Drew Brees | 2013 | NO | 16 | 39 | 446 | 650 | 68.6 | 5,162 | 7.9 | 322.6 | 6.0 | 12 | 1.8 | 37 | 244 | 104.7 |
| 17 | | Aaron Rodgers | 2012 | GB | 16 | 39 | 371 | 552 | 67.2 | 4,295 | 7.8 | 268.4 | 7.1 | 8 | 1.4 | 51 | 293 | 108.0 |
| 18 | | Tom Brady | 2011 | NE | 16 | 39 | 401 | 611 | 65.6 | 5,235 | 8.6 | 327.2 | 6.4 | 12 | 2.0 | 32 | 173 | 105.6 |
| 19 |  | Daunte Culpepper | 2004 |  MIN | 16 | 39 | 379 | 548 | 69.2 | 4,717 | 8.6 | 294.8 | 7.1 | 11 | 2.0 | 46 | 238 | 110.9 |
| 20 |  | Brett Favre | 1996 | GB | 16 | 39 | 325 | 543 | 59.9 | 3,899 | 7.2 | 243.7 | 7.2 | 13 | 2.4 | 40 | 241 | 95.8 |
| 21 |  | Matt Ryan | 2016 |  ATL | 16 | 38 | 373 | 534 | 69.9 | 4,944 | 9.3 | 309.0 | 7.1 | 7 | 1.3 | 37 | 235 | 117.1 |
| 22 | | Aaron Rodgers | 2014 | GB | 16 | 38 | 341 | 520 | 65.6 | 4,381 | 8.4 | 273.8 | 7.3 | 5 | 1.0 | 28 | 174 | 112.2 |
| 23 | | Brett Favre | 1995 | GB | 16 | 38 | 359 | 570 | 63.0 | 4,413 | 7.7 | 275.8 | 6.7 | 13 | 2.3 | 33 | 217 | 99.5 |
| 24 | | Drew Brees | 2016 | NO | 16 | 37 | 471 | 673 | 70.0 | 5,208 | 7.7 | 325.5 | 5.5 | 15 | 2.2 | 27 | 184 | 101.7 |
| 25 | | Peyton Manning | 2012 | DEN | 16 | 37 | 400 | 583 | 68.6 | 4,659 | 8.0 | 291.2 | 6.3 | 11 | 1.9 | 21 | 137 | 105.8 |
StatMuse has season-level data for passing touchdowns going back to the 1921 season.
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