I don't have anything for this season, but the Boston Celtics were 2-6 without Jayson Tatum in 2020-21.

boston celtics record without jayson tatum this season
TEAMSEASONGPRECW%MPGPPGRPGAPGSPGBPGTPGFGMFGAFG%3PM3PA3P%FTMFTAFT%MINPTSREBASTSTLBLKTOVPF
Boston CelticsBoston Celtics2020-2182-6.250243.1111.543.522.88.44.813.441.089.645.712.638.033.216.922.475.41,9458923481826738107176