The Memphis Grizzlies have the highest point differential by a team in a game, with a 73 point differential against the Thunder on December 2.

largest point differential in an nba game
Interpreted as:
largest point differential in an NBA regular-season game
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12/2/2021Grizzlies12/17/1991Cavaliers2/27/1998Pacers3/19/1972Lakers11/2/1991Warriors12/25/1960Nationals3/22/2018Hornets12/26/1978Bucks3/19/1977Warriors12/29/1992Kings12/15/1985Bucks5/1/2021Pacers12/8/2018Celtics3/6/1993SuperSonics1/2/1993Kings12/6/1986SuperSonics3/14/1979Bucks2/20/1976Bulls11/12/1966Lakers1/11/2011Lakers4/17/1989Suns11/2/197076ers4/2/2021Raptors11/13/2014Mavericks11/8/2001Timberwolves73686563626261595958585756565656565656555554535353
TEAMDATETMOPPRESULTDIFFMINPTSREBASTSTLBLKTOVFGMFGAFG%3PM3PA3P%FTMFTAFT%PF
Memphis GrizzliesMemphis Grizzlies12/2/2021MEMMEMvsOKCOKC
W
152-79
73240152534116910609662.5193652.8131872.215
Cleveland CavaliersCleveland Cavaliers12/17/1991CLECLEvsMIAMIA
W
148-80
68240148593911595910357.361154.5242982.816
Indiana PacersIndiana Pacers2/27/1998INDINDvsPORPOR
W
124-59
65240124483516517497763.691560.0172277.321
Los Angeles LakersLos Angeles Lakers3/19/1972LALLALvsGSWGSW
W
162-99
6324016273436911361.1243275.021
Golden State WarriorsGolden State Warriors11/2/1991GSWGSWvsSACSAC
W
153-91
622401536038154225810157.41520.0364090.015
Syracuse NationalsSyracuse Nationals12/25/1960SYRSYRvsNYKNYK
W
162-100
6224016265323786.528
Charlotte HornetsCharlotte Hornets3/22/2018CHACHAvsMEMMEM
W
140-79
6124014053251048499253.3194047.5232785.217
Milwaukee BucksMilwaukee Bucks12/26/1978MILMILvsDETDET
W
143-84
5924014354531711216510760.7131776.512
Golden State WarriorsGolden State Warriors3/19/1977GSWGSWvsINDIND
W
150-91
5924015071391310206512253.3202676.920
Sacramento KingsSacramento Kings12/29/1992SACSACvsDALDAL
W
139-81
58240139574014818509751.561735.3333789.221
Milwaukee BucksMilwaukee Bucks12/15/1985MILMILvsSACSAC
W
140-82
58240140383413219548166.72366.7303683.322
Indiana PacersIndiana Pacers5/1/2021INDIND@OKCOKC
W
152-95
57240152534171117578765.5213363.6172277.322
Boston CelticsBoston Celtics12/8/2018BOSBOS@CHICHI
W
133-77
5624013354341047509353.8224351.2111573.314
Seattle SuperSonicsSeattle SuperSonics3/6/1993SEASEAvsPHIPHI
W
149-93
562401494838138136410262.791369.2121770.619
Sacramento KingsSacramento Kings1/2/1993SACSACvsPHIPHI
W
154-98
562401544638229136110657.591752.9233174.225
Seattle SuperSonicsSeattle SuperSonics12/6/1986SEASEA@HOUHOU
W
136-80
56240136552614719529157.11333.3313393.921
Milwaukee BucksMilwaukee Bucks3/14/1979MILMILvsNOJNOJ
W
158-102
5624015851452176910665.1202290.921
Chicago BullsChicago Bulls2/20/1976CHICHIvsPORPOR
W
130-74
5624013060291435611150.5182766.719
Los Angeles LakersLos Angeles Lakers11/12/1966LALLALvsDETDET
W
144-88
562401447532539754.6384486.419
Los Angeles LakersLos Angeles Lakers1/11/2011LALLALvsCLECLE
W
112-57
55240112532511712468653.5102050.0101566.714
Phoenix SunsPhoenix Suns4/17/1989PHXPHXvsSACSAC
W
140-85
55240140483316413519056.76966.7324178.019
Philadelphia 76ersPhiladelphia 76ers11/2/1970PHIPHIvsCLECLE
W
141-87
542401415435529256.5375369.823
Toronto RaptorsToronto Raptors4/2/2021TORTORvsGSWGSW
W
130-77
53240130532614812478853.4153542.9212584.017
Dallas MavericksDallas Mavericks11/13/2014DALDALvsPHIPHI
W
123-70
53240123513314515418051.3113234.4303683.325
Minnesota TimberwolvesMinnesota Timberwolves11/8/2001MINMINvsCHICHI
W
127-74
5324012739391079528164.251145.5182281.824
Chicago BullsChicago Bulls2/1/1983CHICHIvsHOUHOU
W
129-76
5324012954331538549358.100212875.015
Denver NuggetsDenver Nuggets3/16/2008DENDENvsSEASEA
W
168-116
5224016851441210146110160.4163151.6303585.719
Detroit PistonsDetroit Pistons1/31/2003DETDET@BOSBOS
W
118-66
522401184924739417951.9123237.5243177.415
Charlotte HornetsCharlotte Hornets2/27/1992CHACHAvsPHIPHI
W
136-84
52240136522915312488953.93560.0374680.423
Houston RocketsHouston Rockets10/18/1978HOUHOUvsNJNNJN
W
139-87
522401396140116185610056.0273871.118