LeBron James has the most games by a player younger than 21 with 40+ points, with 8 games.

Interpreted as:

most 40 or more point regular-season games by a player before 21 years old

	NAME	GP	PTS	MPG	PPG	RPG	APG	SPG	BPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TPG	MIN	REB	AST	STL	BLK	TOV	PF	+/-
1	LeBron James L. James	8	357	45.5	44.6	7.4	7.5	2.3	0.3	15.4	26.9	57.2	3.6	7.3	50.0	10.3	11.4	90.1	70.0	1.4	6.0	3.8	364	59	60	18	2	30	19	+43
2	Anthony Edwards A. Edwards	5	221	39.2	44.2	6.8	4.6	1.8	0.8	15.6	27.0	57.8	6.0	12.4	48.4	7.0	10.2	68.6	70.2	1.8	5.0	2.8	196	34	23	9	4	14	13	+49
3	Victor Wembanyama V. Wembanyama	4	174	36.9	43.5	12.5	4.5	1.5	3.0	15.0	26.5	56.6	6.3	14.0	44.6	7.3	9.3	78.4	71.1	2.0	10.5	3.5	148	50	18	6	12	14	6	+38
4	Jalen Green J. Green	4	165	37.8	41.3	3.0	4.0	0.5	0.3	14.8	24.3	60.8	5.0	10.5	47.6	6.8	9.0	75.0	73.1	0.5	2.5	2.3	151	12	16	2	1	9	5	+24
5	Luka Dončić L. Dončić	4	166	35.2	41.5	9.5	11.0	0.8	0.3	13.8	26.3	52.4	4.8	12.8	37.3	9.3	12.8	72.5	65.1	1.3	8.3	3.8	141	38	44	3	1	15	14	+64
6	Kevin Durant K. Durant	4	176	43.8	44.0	10.3	4.0	1.0	1.5	14.8	25.5	57.8	3.3	6.0	54.2	11.3	12.5	90.0	71.0	1.3	9.0	3.3	175	41	16	4	6	13	9	+8
7	John Drew J. Drew	3	125	37.7	41.7	21.0	4.3			14.3	24.3	58.9				13.0	17.3	75.0	65.2				113	63	13				13
8	Kyrie Irving K. Irving	2	81	38.6	40.5	4.0	5.0	1.5	0.0	15.5	24.5	63.3	3.0	5.5	54.5	6.5	7.0	92.9	73.4	0.5	3.5	4.0	77	8	10	3	0	8	8	+19
9	GG Jackson	1	44	44.1	44.0	12.0	1.0	2.0	1.0	17.0	36.0	47.2	4.0	13.0	30.8	6.0	7.0	85.7	56.3	6.0	6.0	3.0	44	12	1	2	1	3	1	-13
10	Kenneth Lofton Jr. K. Lofton Jr.	1	42	40.4	42.0	14.0	0.0	1.0	0.0	17.0	25.0	68.0	0.0	2.0	0.0	8.0	12.0	66.7	69.4	6.0	8.0	2.0	40	14	0	1	0	2	3	-17
11	Kevin Porter Jr. K. Porter Jr.	1	50	41.1	50.0	5.0	11.0	0.0	1.0	16.0	26.0	61.5	9.0	15.0	60.0	9.0	11.0	81.8	81.1	0.0	5.0	5.0	41	5	11	0	1	5	5	+19
12	Jaren Jackson Jr. J. Jackson Jr.	1	43	29.3	43.0	5.0	1.0	0.0	1.0	14.0	21.0	66.7	9.0	15.0	60.0	6.0	9.0	66.7	86.1	0.0	5.0	3.0	29	5	1	0	1	3	5	-5
13	Trae Young T. Young	1	49	55.8	49.0	8.0	16.0	1.0	1.0	17.0	33.0	51.5	6.0	13.0	46.2	9.0	11.0	81.8	64.7	1.0	7.0	9.0	56	8	16	1	1	9	2	-9
14	Devin Booker D. Booker	1	70	45.0	70.0	8.0	6.0	3.0	1.0	21.0	40.0	52.5	4.0	11.0	36.4	24.0	26.0	92.3	68.0	2.0	6.0	5.0	45	8	6	3	1	5	3	-6
15	Brandon Jennings B. Jennings	1	55	40.7	55.0	5.0	5.0	0.0	0.0	21.0	34.0	61.8	7.0	8.0	87.5	6.0	8.0	75.0	73.3	1.0	4.0	4.0	41	5	5	0	0	4	1	+11
16	Eric Gordon E. Gordon	1	41	43.6	41.0	2.0	4.0	1.0	0.0	12.0	19.0	63.2	5.0	7.0	71.4	12.0	14.0	85.7	81.5	0.0	2.0	2.0	44	2	4	1	0	2	4	0
17	Carmelo Anthony C. Anthony	1	41	44.0	41.0	5.0	0.0	2.0	1.0	19.0	29.0	65.5	2.0	3.0	66.7	1.0	1.0	100.0	69.6	0.0	5.0	4.0	44	5	0	2	1	4	5	+3
18	Shaquille O'Neal S. O'Neal	1	46	49.0	46.0	21.0	3.0	0.0	5.0	19.0	25.0	76.0	0.0	0.0		8.0	16.0	50.0	71.8	3.0	18.0	6.0	49	21	3	0	5	6	5
19	Cliff Robinson C. Robinson	1	45	36.0	45.0	10.0	4.0			19.0	28.0	67.9	1.0			6.0	7.0	85.7	72.4				36	10	4				3
20	Bernard King B. King	1	41	43.0	41.0	14.0	2.0			16.0	28.0	57.1				9.0	11.0	81.8	62.4				43	14	2				3
21	Carl Braun C. Braun	1	47		47.0					18.0	35.0	51.4				11.0