James Harden has the most games by an active player with 45+ points, with 42 games.

Interpreted as:

most 45 or more point regular-season games by active players

	NAME	GP	PTS	MPG	PPG	RPG	APG	SPG	BPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TPG	MIN	REB	AST	STL	BLK	TOV	PF	+/-
1	James Harden J. Harden	42	2,153	40.1	51.3	7.1	7.4	2.2	0.6	15.0	28.2	53.2	6.4	13.7	46.4	14.9	16.6	89.4	72.1	1.3	5.9	5.0	1,686	300	312	92	25	212	124	+484
2	Stephen Curry S. Curry	36	1,783	36.8	49.5	5.2	5.4	1.6	0.3	16.2	27.3	59.3	9.3	16.4	57.0	7.9	8.4	94.0	80.0	0.6	4.6	3.1	1,327	187	193	57	10	113	73	+379
3	LeBron James L. James	27	1,349	41.9	50.0	8.0	6.9	1.7	0.9	17.2	28.5	60.3	4.9	8.8	55.9	10.7	13.0	82.3	73.1	1.4	6.5	3.2	1,131	215	185	45	23	86	51	+216
4	Giannis Antetokounmpo G. Antetokounmpo	21	1,049	37.0	50.0	13.3	4.8	1.2	1.1	18.0	28.0	64.3	1.5	4.2	36.4	12.4	16.3	76.1	71.0	2.8	10.5	3.0	776	280	100	26	23	63	54	+182
5	Kevin Durant K. Durant	21	1,024	43.1	48.8	8.3	4.8	1.5	1.0	16.2	28.5	56.8	4.4	8.6	51.4	12.0	13.2	90.6	71.0	0.9	7.4	3.7	905	175	101	32	21	77	53	+79
6	Damian Lillard D. Lillard	20	1,060	39.3	53.0	4.6	7.9	1.4	0.2	16.4	28.2	58.1	7.8	14.3	54.7	12.5	13.3	94.3	78.0	0.4	4.2	2.4	787	92	157	28	4	48	29	+213
7	Russell Westbrook R. Westbrook	20	966	39.4	48.3	9.7	8.1	2.0	0.3	16.5	32.4	50.9	3.6	9.0	39.7	11.8	13.8	85.5	62.8	1.6	8.1	4.8	788	193	162	39	5	95	54	+58
8	Luka Dončić L. Dončić	18	898	39.5	49.9	10.4	9.1	1.9	0.6	16.8	28.0	59.9	6.2	11.8	52.8	10.1	12.9	78.1	74.0	0.8	9.6	3.8	710	187	163	34	11	69	47	+185
9	Devin Booker D. Booker	17	878	39.0	51.6	5.4	5.9	1.2	0.5	18.5	30.4	61.0	4.4	9.4	47.2	10.2	11.5	88.7	72.9	0.9	4.5	3.2	663	92	100	21	8	54	46	+112
10	Joel Embiid J. Embiid	16	809	35.8	50.6	13.4	4.7	1.6	2.3	17.7	27.3	64.8	1.1	3.2	35.3	14.1	15.8	88.9	73.8	3.3	10.1	3.1	573	214	75	25	37	49	44	+234
11	Kyrie Irving K. Irving	15	745	39.4	49.7	4.6	5.0	1.8	0.5	16.7	27.7	60.3	6.9	11.7	59.1	9.3	10.0	92.7	77.3	0.8	3.8	2.1	591	69	75	27	7	31	44	+193
12	Anthony Davis A. Davis	14	681	41.4	48.6	15.8	2.9	2.3	2.3	18.0	30.7	58.6	1.4	3.4	39.6	11.3	12.9	87.3	66.8	4.6	11.2	1.9	579	221	41	32	32	26	30	+134
13	Nikola Jokić N. Jokić	11	552	40.7	50.2	11.8	8.5	1.8	1.3	18.1	28.8	62.8	3.5	6.5	54.9	10.5	12.6	82.7	73.0	3.9	7.9	3.4	448	130	93	20	14	37	33	+117
14	Trae Young T. Young	11	527	41.5	47.9	4.0	10.5	1.4	0.2	14.4	27.4	52.5	5.9	12.6	46.8	13.3	14.5	91.3	70.9	0.5	3.5	5.4	456	44	116	15	2	59	17	+71
15	Bradley Beal B. Beal	11	546	40.2	49.6	4.4	4.1	1.3	0.5	17.3	31.1	55.6	4.7	9.8	48.1	10.4	11.4	91.2	68.8	1.9	2.5	3.6	442	48	45	14	6	40	31	-23
16	Jayson Tatum J. Tatum	9	454	40.7	50.4	9.6	4.9	0.3	0.8	16.3	28.8	56.8	6.7	12.0	55.6	11.1	12.3	90.1	73.7	1.6	8.0	2.2	367	86	44	3	7	20	24	+101
17	Shai Gilgeous-Alexander S. Gilgeous-Alexander	8	400	38.4	50.0	5.8	6.1	2.3	1.3	16.1	27.9	57.8	3.4	7.3	46.6	14.4	15.5	92.7	72.1	0.9	4.9	1.9	307	46	49	18	10	15	21	+103
18	Donovan Mitchell D. Mitchell	8	391	39.3	48.9	6.4	6.4	2.0	0.4	15.6	28.6	54.6	5.9	12.8	46.1	11.8	13.5	87.0	70.7	1.9	4.5	3.1	315	51	51	16	3	25	15	+95
19	Paul George P. George	8	368	41.7	46.0	9.5	5.3	1.8	0.1	15.0	27.3	55.0	6.3	12.8	49.0	9.8	11.5	84.8	71.2	1.4	8.1	2.5	334	76	42	14	1	20	29	+27
20	Jalen Brunson J. Brunson	7	349	40.3	49.9	3.7	7.0	1.3	0.1	17.4	31.0	56.2	5.0	10.7	46.7	10.0	11.4	87.5	69.2	1.0	2.7	2.6	282	26	49	9	1	18	7	+59
21	DeMar DeRozan D. DeRozan	7	333	42.8	47.6	7.1	5.1	1.7	0.6	15.4	25.4	60.7	2.3	5.0	45.7	14.4	15.9	91.0	73.4	1.0	6.1	2.0	299	50	36	12	4	14	21	+76
22	Zach LaVine Z. LaVine	6	288	41.0	48.0	6.7	4.2	0.8	0.2	17.2	29.7	57.9	8.7	14.3	60.5	5.0	6.2	81.1	74.1	1.0	5.7	4.8	246	40	25	5	1	29	15	+26
23	Jamal Murray J. Murray	6	296	38.6	49.3	4.8	4.8	1.2	0.2	18.8	27.7	68.1	7.3	11.2	65.7	4.3	4.8	89.7	82.8	0.5	4.3	3.2	231	29	29	7	1	19	10	+89
24	Tyrese Maxey T. Maxey	5	252	45.7	50.4	4.6	5.2	1.2	1.8	17.6	32.4	54.3	5.4	12.4	43.5	9.8	11.0	89.1	67.7	0.6	4.0	2.6	229	23	26	6	9	13	14	+53
25	Anthony Edwards A. Edwards	5	250	40.0	50.0	6.6	5.0	0.8	0.2	15.6	28.6	54.5	7.0	13.8	50.7	11.8	13.4	88.1	72.5	1.8	4.8	4.2	200	33	25	4	1	21	9	+35