Dwight Howard has the most career games by a player younger than 28, with 718 games.

Interpreted as:

most 50 pound regular-season games before turning 28 years old by a player

	NAME	GP	MPG	PPG	RPG	APG	SPG	BPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TPG	MIN	PTS	REB	AST	STL	BLK	TOV	PF	+/-
1	Dwight Howard D. Howard	718	36.1	18.2	12.9	1.5	1.0	2.2	6.4	11.2	57.7	0.0	0.1	5.0	5.3	9.3	57.6	59.8	3.6	9.3	3.1	25,892	13,084	9,287	1,080	725	1,566	2,221	2,369	+2477
2	LeBron James L. James	717	39.8	27.6	7.2	6.9	1.7	0.8	9.9	20.3	48.6	1.3	4.0	33.4	6.5	8.7	74.5	57.1	1.2	6.0	3.3	28,558	19,771	5,180	4,943	1,238	607	2,378	1,368	+3580
3	Kobe Bryant K. Bryant	707	35.7	23.9	5.1	4.5	1.5	0.6	8.3	18.4	45.1	1.1	3.4	33.6	6.1	7.3	83.4	55.2	1.2	3.9	2.9	25,239	16,866	3,634	3,148	1,059	431	2,030	1,906	+2532
4	Josh Smith J. Smith	695	34.2	15.3	8.0	3.2	1.3	2.1	6.0	12.9	46.3	0.4	1.5	28.2	3.0	4.6	65.2	51.4	2.1	5.9	2.5	23,763	10,643	5,536	2,236	890	1,471	1,768	1,965	+62
5	Kevin Garnett K. Garnett	693	38.2	20.0	10.8	4.4	1.4	1.8	8.1	16.6	48.8	0.2	0.7	30.3	3.6	4.7	76.1	53.5	2.8	8.0	2.6	26,462	13,864	7,493	3,059	968	1,231	1,780	1,758	+2264
6	Tracy McGrady T. McGrady	683	34.9	22.4	6.3	4.6	1.4	1.0	8.1	18.5	43.9	1.3	3.8	34.2	4.9	6.5	75.2	52.5	1.7	4.6	2.3	23,841	15,317	4,284	3,138	929	699	1,601	1,356	+930
7	Giannis Antetokounmpo G. Antetokounmpo	675	32.6	22.1	9.4	4.6	1.2	1.3	8.0	15.0	53.5	0.7	2.4	28.6	5.4	7.6	71.3	60.4	1.7	7.7	2.9	21,979	14,927	6,364	3,124	780	876	1,954	2,034	+2105
8	Tony Parker T. Parker	668	33.0	16.6	3.1	5.6	1.0	0.1	6.6	13.5	49.0	0.5	1.5	31.2	3.0	4.1	72.8	54.5	0.4	2.6	2.5	22,063	11,113	2,038	3,772	635	52	1,682	1,252	+3443
9	Thaddeus Young T. Young	665	30.6	13.9	5.9	1.5	1.4	0.4	6.0	12.0	49.7	0.4	1.2	31.9	1.6	2.3	68.8	53.5	2.0	3.9	1.5	20,357	9,251	3,916	1,013	944	266	970	1,478	-510
10	Carmelo Anthony C. Anthony	646	36.2	24.7	6.3	3.1	1.1	0.5	8.8	19.3	45.6	0.8	2.6	32.2	6.3	7.8	80.5	54.4	1.9	4.4	3.0	23,375	15,926	4,091	2,010	721	299	1,934	1,939	+1371
11	Andre Drummond A. Drummond	645	30.7	14.5	13.7	1.4	1.4	1.5	6.1	11.4	53.8	0.0	0.2	13.5	2.3	4.8	47.0	53.8	4.7	9.0	2.0	19,830	9,358	8,839	872	898	987	1,296	2,056	-663
12	Kevin Durant K. Durant	641	37.8	27.4	7.0	3.7	1.2	1.0	9.2	19.1	48.3	1.8	4.7	38.0	7.2	8.1	88.2	60.5	0.8	6.2	3.2	24,207	17,566	4,518	2,363	774	639	2,083	1,213	+1964
13	Bismack Biyombo B. Biyombo	636	20.2	5.1	6.2	0.5	0.3	1.3	1.9	3.7	52.0	0.0	0.0	0.0	1.3	2.2	57.5	54.8	2.0	4.3	0.9	12,865	3,273	3,968	338	159	852	577	1,408	-1891
14	Shareef Abdur-Rahim S. Abdur-Rahim	636	37.1	20.0	8.2	2.8	1.1	0.8	7.2	15.3	46.7	0.2	0.7	30.4	5.4	6.7	81.5	54.7	2.5	5.8	2.9	23,615	12,707	5,228	1,756	690	539	1,836	1,742	-2663
15	Stephon Marbury S. Marbury	636	38.6	20.5	3.1	8.3	1.3	0.2	7.3	16.9	43.4	1.2	3.7	31.6	4.7	5.9	78.8	52.6	0.8	2.3	3.2	24,556	13,039	1,949	5,264	808	100	2,045	1,532	-402
16	Shawn Kemp S. Kemp	636	29.9	16.3	9.6	1.7	1.2	1.5	5.9	11.4	52.0	0.0	0.1	28.6	4.4	6.1	73.0	58.0	3.4	6.1	2.9	18,989	10,362	6,088	1,112	790	976	1,834	2,424	+509
17	Andrew Wiggins A. Wiggins	635	34.8	19.1	4.5	2.3	1.0	0.7	7.1	15.9	44.9	1.5	4.1	35.4	3.4	4.7	72.0	53.2	1.3	3.2	2.0	22,126	12,152	2,835	1,478	640	427	1,239	1,405	-310
18	Isiah Thomas I. Thomas	635	36.7	20.3	3.7	9.8			7.7	16.7	46.3	0.3			4.4	5.8	76.1	52.5				23,274	12,862	2,372	6,220				2,104
19	Enes Kanter Freedom E. Kanter Freedom	634	21.8	11.6	7.6	0.9	0.4	0.5	4.8	8.8	54.2	0.1	0.2	28.7	2.0	2.6	77.6	58.5	2.9	4.7	1.5	13,839	7,362	4,830	539	257	298	974	1,381	-561
20	Derrick Favors D. Favors	632	25.7	11.6	7.2	1.1	0.8	1.3	4.7	8.9	52.5	0.1	0.3	21.0	2.2	3.2	66.4	55.9	2.5	4.7	1.4	16,268	7,320	4,547	701	498	813	895	1,664	-52
21	Spencer Hawes S. Hawes	630	23.4	8.9	5.9	1.9	0.4	1.0	3.7	8.1	45.6	0.5	1.5	35.3	1.0	1.4	70.8	51.1	1.5	4.4	1.5	14,745	5,595	3,702	1,190	249	622	922	1,632	-1512
22	Chris Bosh C. Bosh	629	36.8	19.9	9.2	2.1	0.8	1.1	7.1	14.3	49.3	0.1	0.3	28.6	5.7	7.1	79.9	57.0	2.5	6.6	2.2	23,132	12,494	5,757	1,340	493	681	1,353	1,608	+1139
23	Mark Olberding M. Olberding	627	25.9	10.3	5.4	2.5			3.6	7.4	48.7	0.0			3.1	3.8	80.6	56.6				16,208	6,456	3,387	1,591				2,167
24	Marvin Williams M. Williams	626	29.1	10.8	5.1	1.3	0.8	0.5	3.9	8.7	44.7	0.6	1.7	33.5	2.4	3.0	80.4	53.7	1.3	3.8	1.1	18,223	6,748	3,179	809	476	282	693	1,367	-443
25	Al Harrington A. Harrington	625	29.5	13.1	5.8	1.8	0.9	0.3	5.1	11.3	45.3	0.6	1.6	36.0	2.3	3.2	71.4	51.6	1.7	4.1	2.0	18,456	8,188	3,625	1,153	562	167	1,255	2,064	-519