LeBron James has dropped the most career points in game ones, with 1,425 points.

Interpreted as:

NBA most points by a player in a game 1 player

	NAME	PTS	GP	MPG	PPG	RPG	APG	SPG	BPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TPG	MIN	REB	AST	STL	BLK	TOV	PF	+/-
1	LeBron James L. James	1,425	55	40.4	25.9	9.0	7.0	1.5	1.1	9.6	19.4	49.6	1.3	4.2	29.6	5.4	7.3	74.2	57.2	1.7	7.3	3.5	2,223	496	386	82	60	191	106	+92
2	Michael Jordan M. Jordan	1,258	37	41.2	34.0	6.4	5.6	2.1	0.8	12.7	25.5	49.7	0.8	2.3	33.7	7.8	9.1	85.5	57.5	1.4	5.1	2.9	1,523	238	206	79	30	108	114	+68
3	Shaquille O'Neal S. O'Neal	1,167	44	38.2	26.5	12.0	2.6	0.7	2.5	10.4	18.7	55.7	0.0	0.0		5.8	10.8	53.5	56.7	4.5	7.6	3.3	1,680	529	114	32	108	145	154	+123
4	Tim Duncan T. Duncan	1,113	48	37.7	23.2	11.5	3.3	0.8	2.3	9.1	17.2	53.0	0.0	0.1	25.0	4.9	7.4	66.9	56.7	3.2	8.3	2.5	1,809	551	158	40	109	122	123	+377
5	Kareem Abdul-Jabbar K. Abdul-Jabbar	1,111	49	35.0	22.7	9.7	2.8	0.9	2.4	9.4	17.0	55.2	0.0	0.0	0.0	3.9	5.2	75.1	58.8			2.3	1,713	477	138	36	99	83	150
6	Kobe Bryant K. Bryant	1,108	43	38.0	25.8	4.6	4.3	1.2	0.8	9.2	21.0	43.8	0.9	3.2	28.5	6.4	7.8	82.2	52.6	0.9	3.7	2.6	1,636	198	187	50	36	111	126	+112
7	Kevin Durant K. Durant	924	32	38.8	28.9	8.1	4.0	0.8	1.4	10.0	20.9	47.8	1.8	5.1	34.1	7.2	8.3	87.1	58.9	0.8	7.3	3.0	1,242	260	129	27	45	95	79	+129
8	Karl Malone K. Malone	885	38	40.1	23.3	10.6	3.0	1.6	0.7	8.8	19.3	45.6	0.1	0.2	33.3	5.6	7.8	72.0	51.2	2.4	8.2	3.1	1,524	402	113	60	25	118	110	+64
9	Tony Parker T. Parker	780	42	35.2	18.6	3.2	5.8	1.1	0.0	7.4	15.8	46.6	0.5	1.4	37.3	3.3	4.3	76.7	52.4	0.6	2.6	2.5	1,478	133	244	46	1	107	71	+303
10	Scottie Pippen S. Pippen	759	43	39.3	17.7	7.3	5.1	1.9	1.1	6.4	14.4	44.3	1.0	3.2	32.1	3.9	5.0	78.4	53.2	1.7	5.5	2.4	1,692	312	220	80	48	103	137	+52
11	Magic Johnson M. Johnson	744	40	37.4	18.6	7.0	12.8	2.2	0.2	6.6	12.9	51.0	0.3	0.9	31.4	5.2	6.3	82.1	59.3			3.2	1,497	280	510	89	9	128	108
12	Hakeem Olajuwon H. Olajuwon	743	29	39.1	25.6	11.0	3.2	2.0	3.3	10.3	18.7	55.4	0.0	0.0	0.0	4.9	6.8	72.2	59.1	3.4	7.6	3.2	1,135	319	94	58	96	92	119	-11
13	Stephen Curry S. Curry	742	28	36.7	26.5	5.8	5.5	1.6	0.2	9.4	19.2	48.8	4.5	10.0	45.2	3.3	3.7	87.5	63.7	0.8	5.0	3.4	1,026	161	155	45	5	96	71	+213
14	James Harden J. Harden	725	31	33.2	23.4	4.5	6.3	1.4	0.3	7.5	16.7	44.5	3.1	7.7	40.3	5.4	6.2	87.4	60.1	0.7	3.8	3.0	1,030	139	194	44	10	93	92	+19
15	Larry Bird L. Bird	722	30	40.7	24.1	10.1	7.3			9.1	18.8	48.7	0.5	1.5	33.3	5.3	5.9	89.8	56.3				1,221	302	219				71
16	Jerry West J. West	721	26		27.7	5.0				9.5	22.7	42.0				8.7	10.7	80.9	50.5					130					80
17	John Havlicek J. Havlicek	717	31		23.1	6.3	5.0			9.4	19.3	48.4				4.4	5.1	87.3	53.7					195	155				88
18	Dirk Nowitzki D. Nowitzki	694	27	39.9	25.7	10.4	2.0	1.0	1.1	8.5	18.2	46.8	0.7	2.3	31.7	7.9	8.6	91.8	58.5	1.9	8.6	2.7	1,077	281	54	27	31	72	70	-130
19	Wilt Chamberlain W. Chamberlain	684	29	47.6	23.6	25.0	4.0			9.6	18.5	51.6				4.5	9.8	45.6	51.6				1,381	724	117				74
20	Dwyane Wade D. Wade	680	32	36.6	21.3	4.2	5.0	1.6	0.9	8.3	17.2	48.1	0.3	1.4	23.9	4.4	5.8	76.2	53.9	1.1	3.1	3.2	1,172	134	161	51	28	102	84	+25
21	Elgin Baylor E. Baylor	662	25		26.5					10.4						5.7	7.7	73.6											81
22	James Worthy J. Worthy	646	30	35.2	21.5	4.9	3.8	1.3	0.6	9.1	16.8	54.3	0.0	0.4	0.0	3.3	4.3	76.6	57.5	1.5	3.4	2.1	1,055	146	113	40	18	64	63
23	Kevin McHale K. McHale	634	32	32.7	19.8	6.9	1.4			7.7	12.8	60.5	0.0	0.1	0.0	4.4	5.4	81.4	65.5				1,047	220	46				102
24	Julius Erving J. Erving	620	28	36.9	22.1	7.6	4.0			8.6	18.2	47.3	0.0	0.4	0.0	4.9	6.4	76.7	52.6				1,034	214	112				70
25	Robert Parish R. Parish	606	36	33.6	16.8	9.8	1.3			7.2	12.9	55.7	0.0	0.0		2.4	3.4	72.7	58.5				1,209	354	46				105