Manu Ginobili scored his most points in a game versus LeBron James against the Cavaliers on February 13, 2008, with 46 points.
| NAME | PTS | DATE | TM | OPP | MIN | REB | AST | STL | BLK | FGM | FGA | FG% | 3PM | 3PA | 3P% | FTM | FTA | FT% | TS% | OREB | DREB | TOV | PF | +/- | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | M. Ginobili | 46 | 2/13/2008 | @ | 41 | 5 | 8 | 3 | 1 | 15 | 20 | 75.0 | 8 | 11 | 72.7 | 8 | 9 | 88.9 | 96.0 | 0 | 5 | 1 | 2 | +12 | ||
| 2 | | M. Ginobili | 31 | 1/17/2008 | vs | 35 | 4 | 4 | 2 | 0 | 10 | 15 | 66.7 | 4 | 6 | 66.7 | 7 | 8 | 87.5 | 83.7 | 1 | 3 | 4 | 3 | +1 | ||
| 3 | | M. Ginobili | 30 | 3/26/2010 | vs | 36 | 6 | 6 | 1 | 0 | 10 | 19 | 52.6 | 3 | 5 | 60.0 | 7 | 8 | 87.5 | 66.6 | 0 | 6 | 3 | 2 | +12 | ||
| 4 | | M. Ginobili | 21 | 3/29/2004 | vs | 24 | 8 | 2 | 1 | 0 | 8 | 15 | 53.3 | 3 | 4 | 75.0 | 2 | 4 | 50.0 | 62.6 | 3 | 5 | 1 | 2 | +8 | ||
| 5 | | M. Ginobili | 21 | 2/20/2004 | @ | 30 | 3 | 2 | 5 | 0 | 8 | 14 | 57.1 | 1 | 4 | 25.0 | 4 | 4 | 100.0 | 66.6 | 0 | 3 | 5 | 2 | -5 | ||
| 6 | | M. Ginobili | 20 | 3/4/2011 | vs | 27 | 3 | 7 | 2 | 0 | 7 | 15 | 46.7 | 3 | 8 | 37.5 | 3 | 4 | 75.0 | 59.7 | 1 | 2 | 0 | 2 | +20 | ||
| 7 | | M. Ginobili | 17 | 2/28/2005 | @ | 30 | 2 | 3 | 1 | 0 | 4 | 9 | 44.4 | 0 | 2 | 0.0 | 9 | 14 | 64.3 | 56.1 | 1 | 1 | 4 | 4 | +9 | ||
| 8 | | M. Ginobili | 14 | 11/3/2006 | vs | 31 | 4 | 1 | 0 | 1 | 5 | 11 | 45.5 | 3 | 7 | 42.9 | 1 | 3 | 33.3 | 56.8 | 0 | 4 | 3 | 3 | -6 | ||
| 9 | | M. Ginobili | 12 | 3/27/2017 | vs | 17 | 3 | 1 | 1 | 0 | 5 | 7 | 71.4 | 2 | 3 | 66.7 | 0 | 0 | 85.7 | 1 | 2 | 0 | 2 | +12 | |||
| 10 | | M. Ginobili | 12 | 3/14/2011 | @ | 31 | 6 | 5 | 1 | 1 | 4 | 9 | 44.4 | 0 | 3 | 0.0 | 4 | 6 | 66.7 | 51.5 | 1 | 5 | 3 | 3 | -21 | ||
| 11 | | M. Ginobili | 12 | 2/13/2006 | @ | 28 | 7 | 3 | 0 | 0 | 5 | 11 | 45.5 | 0 | 2 | 0.0 | 2 | 3 | 66.7 | 48.7 | 0 | 7 | 3 | 5 | -7 | ||
| 12 | | M. Ginobili | 10 | 1/14/2016 | vs | 26 | 3 | 1 | 1 | 1 | 4 | 12 | 33.3 | 0 | 4 | 0.0 | 2 | 2 | 100.0 | 38.8 | 0 | 3 | 1 | 3 | +4 | ||
| 13 | | M. Ginobili | 10 | 11/4/2005 | vs | 22 | 1 | 4 | 0 | 0 | 4 | 8 | 50.0 | 1 | 3 | 33.3 | 1 | 2 | 50.0 | 56.3 | 0 | 1 | 2 | 2 | +18 | ||
| 14 | | M. Ginobili | 8 | 1/21/2017 | @ | 20 | 2 | 3 | 0 | 0 | 3 | 9 | 33.3 | 2 | 6 | 33.3 | 0 | 0 | 44.4 | 1 | 1 | 1 | 4 | -5 | |||
| 15 | | M. Ginobili | 7 | 11/19/2014 | @ | 31 | 3 | 5 | 0 | 0 | 3 | 7 | 42.9 | 0 | 1 | 0.0 | 1 | 2 | 50.0 | 44.4 | 0 | 3 | 0 | 2 | +1 | ||
| 16 | | M. Ginobili | 6 | 1/30/2016 | @ | 18 | 2 | 1 | 1 | 0 | 2 | 10 | 20.0 | 2 | 4 | 50.0 | 0 | 0 | 30.0 | 0 | 2 | 0 | 3 | -10 | |||
| 17 | | M. Ginobili | 6 | 3/6/2014 | vs | 20 | 0 | 4 | 0 | 0 | 3 | 6 | 50.0 | 0 | 2 | 0.0 | 0 | 0 | 50.0 | 0 | 0 | 1 | 4 | +10 | |||
| 18 | | M. Ginobili | 6 | 1/2/2007 | @ | 29 | 6 | 3 | 0 | 1 | 1 | 8 | 12.5 | 0 | 5 | 0.0 | 4 | 5 | 80.0 | 29.4 | 0 | 6 | 3 | 3 | 0 | ||
| 19 | | M. Ginobili | 4 | 4/5/2009 | @ | 23 | 4 | 4 | 2 | 0 | 2 | 9 | 22.2 | 0 | 6 | 0.0 | 0 | 0 | 22.2 | 1 | 3 | 0 | 4 | -10 | |||
| 20 | | M. Ginobili | 3 | 1/26/2014 | @ | 25 | 1 | 1 | 0 | 1 | 1 | 7 | 14.3 | 0 | 2 | 0.0 | 1 | 1 | 100.0 | 20.2 | 0 | 1 | 2 | 2 | -21 | ||
| 21 | | M. Ginobili | 2 | 12/11/2004 | vs | 23 | 3 | 4 | 1 | 0 | 1 | 5 | 20.0 | 0 | 0 | 0 | 0 | 20.0 | 0 | 3 | 3 | 1 | +7 |
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