Damian Lillard had his highest plus/minus in a game versus the Thunder on April 3, 2021, at +42.

Interpreted as:

highest +/- in a regular-season game in damian lillards career

	NAME	+/-	DATE	TM		OPP	MIN	PTS	REB	AST	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF
1	Damian Lillard D. Lillard	+42	4/3/2021	POR	vs	OKC	25	16	3	6	3	0	6	15	40.0	3	7	42.9	1	1	100.0	51.8	1	2	3	1
2	Damian Lillard D. Lillard	+41	2/27/2024	MIL	vs	CHA	25	23	9	7	0	0	8	14	57.1	4	9	44.4	3	3	100.0	75.1	0	9	3	3
3	Damian Lillard D. Lillard	+40	11/21/2014	POR	vs	CHI	26	21	6	9	1	0	7	9	77.8	4	4	100.0	3	3	100.0	101.7	0	6	4	0
4	Damian Lillard D. Lillard	+37	2/25/2024	MIL	@	PHI	36	24	7	9	2	0	8	15	53.3	4	8	50.0	4	4	100.0	71.6	0	7	5	4
5	Damian Lillard D. Lillard	+37	4/1/2018	POR	vs	MEM	33	27	3	9	2	0	7	15	46.7	2	8	25.0	11	11	100.0	68.0	1	2	0	0
6	Damian Lillard D. Lillard	+35	12/6/2013	POR	vs	UTA	25	21	3	6	1	1	7	9	77.8	5	6	83.3	2	2	100.0	106.3	1	2	3	1
7	Damian Lillard D. Lillard	+34	10/18/2017	POR	@	PHX	30	27	5	5	1	3	10	20	50.0	4	6	66.7	3	3	100.0	63.3	3	2	0	1
8	Damian Lillard D. Lillard	+33	2/9/2024	MIL	vs	CHA	29	26	4	8	3	0	9	18	50.0	2	8	25.0	6	6	100.0	63.0	0	4	0	1
9	Damian Lillard D. Lillard	+33	1/1/2021	POR	@	GSW	35	34	4	8	1	0	11	21	52.4	6	10	60.0	6	6	100.0	71.9	0	4	1	3
10	Damian Lillard D. Lillard	+33	3/8/2013	POR	@	SAS	40	35	3	9	2	0	12	20	60.0	3	4	75.0	8	8	100.0	74.4	1	2	0	3
11	Damian Lillard D. Lillard	+32	4/27/2021	POR	@	IND	31	23	4	6	1	0	6	14	42.9	4	8	50.0	7	7	100.0	67.3	0	4	3	1
12	Damian Lillard D. Lillard	+31	12/6/2018	POR	vs	PHX	28	25	5	8	1	1	8	14	57.1	3	5	60.0	6	7	85.7	73.2	1	4	4	1
13	Damian Lillard D. Lillard	+30	12/4/2022	POR	vs	IND	32	21	4	6	1	1	7	16	43.8	5	10	50.0	2	2	100.0	62.2	0	4	4	4
14	Damian Lillard D. Lillard	+30	2/21/2019	POR	@	BKN	36	13	8	8	2	0	5	21	23.8	2	9	22.2	1	1	100.0	30.3	4	4	1	2
15	Damian Lillard D. Lillard	+30	12/20/2014	POR	@	NOP	28	17	3	7	1	0	6	12	50.0	3	6	50.0	2	2	100.0	66.0	0	3	1	2
16	Damian Lillard D. Lillard	+30	12/14/2013	POR	@	PHI	26	16	1	6	0	0	5	9	55.6	4	6	66.7	2	2	100.0	81.0	0	1	3	3
17	Damian Lillard D. Lillard	+29	12/17/2022	POR	@	HOU	33	25	3	10	2	0	7	20	35.0	5	13	38.5	6	8	75.0	53.1	0	3	1	2
18	Damian Lillard D. Lillard	+29	11/6/2021	POR	vs	LAL	31	25	3	6	2	0	9	19	47.4	6	14	42.9	1	2	50.0	62.9	0	3	3	3
19	Damian Lillard D. Lillard	+29	1/3/2020	POR	@	WAS	34	35	3	3	1	0	10	20	50.0	2	6	33.3	13	14	92.9	66.9	0	3	1	1
20	Damian Lillard D. Lillard	+29	1/30/2019	POR	vs	UTA	37	36	8	11	2	0	12	21	57.1	3	7	42.9	9	9	100.0	72.1	0	8	3	2
21	Damian Lillard D. Lillard	+29	3/28/2014	POR	@	CHI	37	16	4	4	1	0	6	14	42.9	3	5	60.0	1	2	50.0	53.8	0	4	1	1
22	Damian Lillard D. Lillard	+28	3/5/2025	MIL	vs	DAL	27	34	3	5	2	0	11	15	73.3	5	8	62.5	7	7	100.0	94.0	0	3	2	0
23	Damian Lillard D. Lillard	+28	1/2/2023	POR	vs	DET	29	19	5	10	4	2	7	14	50.0	3	6	50.0	2	3	66.7	62.0	0	5	2	2
24	Damian Lillard D. Lillard	+28	12/20/2019	POR	vs	ORL	36	36	3	6	1	0	13	21	61.9	7	13	53.8	3	3	100.0	80.6	0	3	5	1
25	Damian Lillard D. Lillard	+28	12/10/2019	POR	vs	NYK	29	31	2	6	0	0	9	15	60.0	8	12	66.7	5	5	100.0	90.1	0	2	3	2