Wilt Chamberlain had the most games with 40+ points, with 271 games.

Interpreted as:

most +40 or more points regular-season games by a player in NBA history

	NAME	GP	PTS	MPG	PPG	RPG	APG	SPG	BPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TPG	MIN	REB	AST	STL	BLK	TOV	PF	+/-
1	Wilt Chamberlain W. Chamberlain	271	13,458		49.7	25.7				20.3	37.4	54.2				9.2	16.1	57.0	55.8					6,968					500
2	Michael Jordan M. Jordan	173	7,813	41.4	45.2	6.5	5.1	2.8	1.1	16.9	29.5	57.2	0.7	1.9	35.0	10.8	12.5	86.2	64.6	1.9	4.6	2.7	7,157	1,116	886	489	192	472	494	+232
3	Kobe Bryant K. Bryant	122	5,501	42.8	45.1	6.1	4.2	1.8	0.6	15.4	30.1	51.1	2.9	6.6	43.8	11.4	13.3	85.7	62.7	1.2	4.9	3.2	5,218	741	512	214	74	396	334	+759
4	James Harden J. Harden	107	4,854	39.5	45.4	7.4	8.1	2.1	0.7	13.3	26.2	50.8	5.6	12.8	44.2	13.1	14.9	87.9	69.2	1.2	6.2	4.8	4,226	788	869	228	79	516	318	+1074
5	Elgin Baylor E. Baylor	88	3,995		45.4					17.1						11.2	13.9	80.5											309
6	LeBron James L. James	79	3,517	41.6	44.5	8.7	7.1	1.7	0.9	15.7	26.6	59.0	3.8	7.3	51.2	9.3	11.8	79.4	70.0	1.6	7.1	3.7	3,286	684	560	136	73	289	145	+651
7	Allen Iverson A. Iverson	79	3,507	44.9	44.4	4.3	6.3	2.3	0.2	15.5	30.5	51.0	2.0	5.0	40.6	11.3	13.6	83.4	60.9	1.0	3.3	3.7	3,546	339	494	185	14	294	177	+443
8	Oscar Robertson O. Robertson	77	3,288		42.7	9.3	10.9			15.0						12.7	14.4	88.2						718	836				268
9	Stephen Curry S. Curry	74	3,352	36.4	45.3	5.3	5.6	1.4	0.3	14.9	25.4	58.5	8.5	15.2	56.1	7.0	7.6	92.9	78.8	0.7	4.7	3.4	2,693	395	416	103	23	248	150	+870
10	Kevin Durant K. Durant	72	3,143	41.4	43.7	8.1	4.6	1.2	1.2	14.8	25.9	57.2	3.8	7.8	48.5	10.2	11.4	89.4	70.5	0.9	7.2	3.8	2,984	584	332	84	86	270	171	+412
11	Kareem Abdul-Jabbar K. Abdul-Jabbar	70	3,073		43.9	16.1	4.2		3.6	17.7			0.0	0.0		8.5	11.6	73.8						1,126	295		89
12	Rick Barry R. Barry	70	3,165	42.8	45.2	8.3	5.3	2.9		17.5	33.3	52.5				10.2	11.3	90.3	59.0			3.2	2,999	578	374	100		19	230
13	George Gervin G. Gervin	68	2,982	40.0	43.9	5.0	2.9	1.3	0.9	17.2	28.9	59.4	0.3	0.9	35.8	9.2	10.8	85.1	65.1				2,722	342	195	91	61		185
14	Jerry West J. West	66	2,891		43.8					15.8						12.2	14.4	84.8
15	Damian Lillard D. Lillard	60	2,713	39.3	45.2	4.9	7.3	1.2	0.3	14.1	25.3	55.7	6.5	12.9	50.2	10.6	11.5	92.6	74.5	0.6	4.3	2.6	2,356	293	438	71	20	156	115	+423
16	Bob McAdoo B. McAdoo	58	2,518		43.4	15.5				17.0	28.3	60.0				9.5	12.0	79.1	64.7					899
17	Giannis Antetokounmpo G. Antetokounmpo	56	2,514	36.6	44.9	13.0	5.5	1.2	1.2	16.5	25.1	65.9	1.3	3.4	39.1	10.5	14.6	72.2	71.3	2.8	10.2	3.3	2,048	728	306	65	69	183	158	+374
18	Dominique Wilkins D. Wilkins	56	2,493	41.0	44.5	7.7	3.0	1.9	0.7	16.4	29.1	56.3	1.2	2.4	50.0	10.6	12.3	86.2	64.5	3.3	4.3	3.0	2,296	429	166	105	39	167	108
19	Adrian Dantley A. Dantley	52	2,271	42.1	43.7	7.1	4.5		0.1	15.8	23.7	66.5	0.0			12.2	14.4	84.6	72.8				2,188	369	236		4		171
20	Luka Dončić L. Dončić	50	2,227	38.8	44.5	9.7	9.0	1.6	0.4	15.0	26.3	57.1	4.9	10.7	45.4	9.6	12.1	79.4	70.4	0.9	8.8	3.8	1,938	486	452	78	22	192	135	+424
21	Russell Westbrook R. Westbrook	50	2,212	39.0	44.2	9.8	8.3	1.6	0.3	15.5	30.1	51.6	3.1	7.8	40.2	10.1	12.2	82.6	62.4	2.0	7.9	5.0	1,949	491	417	78	15	251	141	+74
22	Shaquille O'Neal S. O'Neal	49	2,102	40.6	42.9	13.6	2.5	0.8	2.2	16.9	25.6	66.1	0.0	0.0	0.0	9.1	15.2	60.1	66.5	5.1	8.5	2.7	1,991	668	122	41	108	132	145	+319
23	Joel Embiid J. Embiid	48	2,134	36.2	44.5	13.4	4.4	1.3	2.0	15.0	24.8	60.5	1.5	3.8	38.0	13.0	15.0	86.7	70.8	2.9	10.5	3.3	1,736	641	213	60	97	157	156	+533
24	Larry Bird L. Bird	47	2,077	42.5	44.2	10.7	6.2	1.9		17.2	28.5	60.3	1.5	3.4	44.1	8.3	8.9	93.1	68.1				1,996	504	293	87			117
25	Bob Pettit B. Pettit	47	2,075		44.1					16.1						11.9	14.6	81.6											159