From 2000 through 2026, running backs had their most rushing yards in a game in a 34 to 31 win by the Dolphins over the Bills on December 24, 2016, with 474 yards.
| POSITION | RUSH YDS | DATE | TM | OPP | ATT | YPC | RUSH TD | REC YDS | REC | TRG | AVG | REC TD | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Running Back | 474 | 12/24/2016 | vs | 73 | 6.5 | 3 | 85 | 10 | 12 | 8.5 | 0 | ||
| 2 | Running Back | 463 | 11/1/2009 | vs | 49 | 9.4 | 4 | 8 | 4 | 8 | 2.0 | 0 | ||
| 3 | Running Back | 462 | 12/20/2009 | vs | 69 | 6.7 | 4 | 36 | 5 | 8 | 7.2 | 0 | ||
| 4 | Running Back | 461 | 12/28/2008 | vs | 64 | 7.2 | 5 | 85 | 7 | 12 | 12.1 | 0 | ||
| 5 | Running Back | 441 | 9/30/2007 | @ | 67 | 6.6 | 1 | 43 | 7 | 8 | 6.1 | 0 | ||
| 6 | Running Back | 439 | 12/21/2008 | @ | 73 | 6.0 | 7 | 41 | 5 | 9 | 8.2 | 0 | ||
| 7 | Running Back | 435 | 12/29/2013 | vs | 72 | 6.0 | 3 | 123 | 11 | 17 | 11.2 | 1 | ||
| 8 | Running Back | 425 | 10/18/2009 | vs | 73 | 5.8 | 1 | 92 | 9 | 16 | 10.2 | 0 | ||
| 9 | Running Back | 423 | 10/22/2000 | @ | 58 | 7.3 | 4 | 7 | 3 | 7 | 2.3 | 1 | ||
| 10 | Running Back | 421 | 12/1/2002 | @ | 67 | 6.3 | 3 | 69 | 9 | 18 | 7.7 | 0 | ||
| 11 | Running Back | 417 | 9/24/2023 | @ | 61 | 6.8 | 5 | 128 | 15 | 17 | 8.5 | 3 | ||
| 12 | Running Back | 414 | 10/30/2005 | @ | 58 | 7.1 | 1 | 23 | 8 | 10 | 2.9 | 1 | ||
| 13 | Running Back | 412 | 1/3/2021 | @ | 52 | 7.9 | 2 | 13 | 2 | 3 | 6.5 | 0 | ||
| 14 | Running Back | 412 | 9/30/2007 | vs | 62 | 6.6 | 1 | 85 | 8 | 12 | 10.6 | 0 | ||
| 15 | Running Back | 410 | 10/7/2018 | @ | 52 | 7.9 | 1 | 107 | 12 | 15 | 8.9 | 0 | ||
| 16 | Running Back | 406 | 10/9/2022 | @ | 57 | 7.1 | 5 | 69 | 9 | 10 | 7.7 | 1 | ||
| 17 | Running Back | 405 | 11/22/2015 | @ | 64 | 6.3 | 0 | 91 | 10 | 18 | 9.1 | 2 | ||
| 18 | Running Back | 404 | 12/10/2006 | vs | 57 | 7.1 | 5 | 56 | 6 | 9 | 9.3 | 0 | ||
| 19 | Running Back | 403 | 1/2/2011 | vs | 64 | 6.3 | 4 | 51 | 7 | 10 | 7.3 | 0 | ||
| 20 | Running Back | 400 | 12/23/2012 | @ | 58 | 6.9 | 1 | 36 | 2 | 5 | 18.0 | 0 | ||
| 21 | Running Back | 399 | 12/23/2007 | vs | 70 | 5.7 | 4 | 48 | 3 | 6 | 16.0 | 0 | ||
| 22 | Running Back | 397 | 11/8/2020 | @ | 59 | 6.7 | 2 | 151 | 12 | 16 | 12.6 | 1 | ||
| 23 | Running Back | 397 | 11/4/2007 | @ | 57 | 7.0 | 5 | 79 | 9 | 15 | 8.8 | 0 | ||
| 24 | Running Back | 396 | 11/24/2013 | vs | 76 | 5.2 | 2 | 94 | 13 | 17 | 7.2 | 0 | ||
| 25 | Running Back | 396 | 10/14/2007 | vs | 65 | 6.1 | 3 | 55 | 8 | 15 | 6.9 | 0 | ||
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More Bills Stats
Team Leaders 
PASS
582
Allen
RUSH
192
Cook
REC
225
Kincaid
Team Rankings
PPG
38.5
1st
OPP PPG
31.0
28th
RUSH YDS/G
144.5
6th
PASS YDS/G
291.0
4th
Jets
LAR
NFL 2026 Leaders
NFL 2026 Rankings
NFL Fantasy 2026
NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
2 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
1 | 1 | 0 | .500 | |
0 | 2 | 0 | .000 | |
| NFC North | W | L | T | PCT |
2 | 0 | 0 | 1.000 | |
1 | 1 | 0 | .500 | |
1 | 1 | 0 | .500 | |
1 | 1 | 0 | .500 | |
| NFC South | W | L | T | PCT |
1 | 1 | 0 | .500 | |
1 | 1 | 0 | .500 | |
0 | 2 | 0 | .000 | |
0 | 2 | 0 | .000 | |
| NFC West | W | L | T | PCT |
2 | 0 | 0 | 1.000 | |
2 | 0 | 0 | 1.000 | |
1 | 1 | 0 | .500 | |
0 | 1 | 0 | .000 |
Cowboys
Commanders
Bears
Packers
Saints
Seahawks
49ers
Cardinals| AFC East | W | L | T | PCT |
|---|---|---|---|---|
2 | 0 | 0 | 1.000 | |
1 | 1 | 0 | .500 | |
1 | 1 | 0 | .500 | |
0 | 2 | 0 | .000 | |
| AFC North | W | L | T | PCT |
2 | 0 | 0 | 1.000 | |
1 | 1 | 0 | .500 | |
1 | 1 | 0 | .500 | |
1 | 1 | 0 | .500 | |
| AFC South | W | L | T | PCT |
1 | 1 | 0 | .500 | |
0 | 2 | 0 | .000 | |
0 | 2 | 0 | .000 | |
0 | 2 | 0 | .000 | |
| AFC West | W | L | T | PCT |
2 | 0 | 0 | 1.000 | |
2 | 0 | 0 | 1.000 | |
1 | 1 | 0 | .500 | |
0 | 2 | 0 | .000 |
Steelers