The San Francisco 49ers have a record of 5-8 in the month of October against the NFC South in the regular-season and playoffs all-time.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 10/20/2002 | 0-1 |  SF | @ |  NO | L 27-35 | .000 | 3 | 26 | 418 | 422 | 75.0 | |
| 2 | | 49ers | 10/19/2003 | 1-0 | SF | vs |  TB | W 24-7 | 1.000 | 3 | 22 | 458 | 326 | 23.1 | 50.0 |
| 3 | | 49ers | 10/30/2005 | 1-0 | SF | vs | TB | W 15-10 | 1.000 | 0 | 9 | 208 | 275 | 12.5 | |
| 4 | | 49ers | 10/28/2007 | 0-1 | SF | vs | NO | L 10-31 | .000 | 1 | 15 | 260 | 438 | 52.6 | 0.0 |
| 5 | | 49ers | 10/11/2009 | 0-1 | SF | vs |  ATL | L 10-45 | .000 | 1 | 13 | 279 | 477 | 28.6 | 50.0 |
| 6 | | 49ers | 10/3/2010 | 0-1 | SF | @ | ATL | L 14-16 | .000 | 2 | 17 | 262 | 357 | 50.0 | 100.0 |
| 7 | | 49ers | 10/24/2010 | 0-1 | SF | @ |  CAR | L 20-23 | .000 | 2 | 15 | 282 | 379 | 30.8 | |
| 8 | | 49ers | 10/9/2011 | 1-0 | SF | vs | TB | W 48-3 | 1.000 | 6 | 28 | 418 | 272 | 28.6 | 100.0 |
| 9 | | 49ers | 10/23/2016 | 0-1 | SF | vs | TB | L 17-34 | .000 | 2 | 20 | 273 | 513 | 40.0 | 100.0 |
| 10 | | 49ers | 10/27/2019 | 1-0 | SF | vs | CAR | W 51-13 | 1.000 | 7 | 24 | 388 | 230 | 50.0 | |
| 11 | | 49ers | 10/9/2022 | 1-0 | SF | @ | CAR | W 37-15 | 1.000 | 5 | 22 | 397 | 308 | 58.3 | |
| 12 | | 49ers | 10/16/2022 | 0-1 | SF | @ | ATL | L 14-28 | .000 | 2 | 21 | 346 | 289 | 37.5 | 0.0 |
| 13 | | 49ers | 10/12/2025 | 0-1 | SF | @ | TB | L 19-30 | .000 | 1 | 17 | 363 | 352 | 43.8 | 0.0 |
| Average | .385 | 2.7 | 19.2 | 334.8 | 356.8 | 40.7 | 5.7 | ||||||||
| Total | 5-8 | .385 | 35 | 249 | 4,352 | 4,638 | 40.7 | 45.5 |
More 49ers Stats
Team Rankings
PPG
20.8
24th
OPP PPG
21.3
15th
RUSH YDS/G
82.2
30th
PASS YDS/G
306.3
1st
Rams 
Cardinals 
HOU 
NYG 
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Division Standings
Patriots 
Bills 
Steelers 
Bengals 
Colts 
Jaguars 
Chargers 
Broncos | NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles | 4 | 2 | 0 | .667 |
 Commanders | 3 | 3 | 0 | .500 |
| NFC North | W | L | T | PCT |
 Packers | 3 | 1 | 1 | .700 |
 Lions | 4 | 2 | 0 | .667 |
| NFC South | W | L | T | PCT |
| Buccaneers | 5 | 1 | 0 | .833 |
| Falcons | 3 | 2 | 0 | .600 |
| NFC West | W | L | T | PCT |
| 49ers | 4 | 2 | 0 | .667 |
 Seahawks | 4 | 2 | 0 | .667 |
DAL 
KC 
NYJ 
LV 
TEN 
CHI 
MIA 
CLE 
