The San Francisco 49ers had their most yards from scrimmage in a game versus the Baltimore Colts on December 13, 1953, with 623 yards.
Interpreted as:
49ers most yards from scrimmage in a regular-season game| TEAM | YDS | DATE | TM | OPP | RUSH YDS | ATT | YPC | RUSH TD | REC YDS | REC | TRG | AVG | REC TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 623 | 12/13/1953 | vs | |||||||||||
| 2 | | 49ers | 621 | 10/7/2012 | vs | 311 | 38 | 8.2 | 3 | 310 | 19 | 25 | 16.3 | 3 | ||
| 3 | | 49ers | 608 | 9/13/1992 | vs | 159 | 30 | 5.3 | 1 | 449 | 26 | 17.3 | 3 | |||
| 4 | | 49ers | 590 | 10/18/1992 | vs | 191 | 34 | 5.6 | 5 | 399 | 18 | 22.2 | 3 | |||
| 5 | | 49ers | 590 | 9/25/1988 | @ | 239 | 48 | 5.0 | 0 | 351 | 24 | 14.6 | 5 | |||
| 6 | | 49ers | 571 | 9/15/2019 | @ | 259 | 42 | 6.2 | 2 | 312 | 18 | 26 | 17.3 | 3 | ||
| 7 | | 49ers | 570 | 9/6/1998 | vs | 207 | 24 | 8.6 | 2 | 363 | 26 | 14.0 | 3 | |||
| 8 | | 49ers | 567 | 10/15/1961 | @ | 324 | 51 | 6.4 | 5 | 243 | 13 | 18.7 | 0 | |||
| 9 | | 49ers | 565 | 12/19/1993 | @ | 172 | 37 | 4.6 | 3 | 393 | 20 | 19.7 | 4 | |||
| 10 | | 49ers | 552 | 11/28/1993 | @ | 64 | 25 | 2.6 | 1 | 488 | 28 | 17.4 | 4 | |||
| 11 | | 49ers | 548 | 9/27/1998 | vs | 161 | 31 | 5.2 | 1 | 387 | 28 | 13.8 | 3 | |||
| 12 | | 49ers | 548 | 9/10/1984 | vs | 167 | 40 | 4.2 | 2 | 381 | 24 | 15.9 | 2 | |||
| 13 | | 49ers | 546 | 12/8/2019 | @ | 162 | 24 | 6.8 | 1 | 384 | 27 | 35 | 14.2 | 5 | ||
| 14 | | 49ers | 542 | 12/5/1999 | @ | 105 | 23 | 4.6 | 1 | 437 | 33 | 45 | 13.2 | 3 | ||
| 15 | | 49ers | 541 | 12/10/2023 | vs | 173 | 23 | 7.5 | 2 | 368 | 19 | 27 | 19.4 | 2 | ||
| 16 | | 49ers | 540 | 11/19/1961 | vs | 218 | 34 | 6.4 | 2 | 322 | 11 | 29.3 | 3 | |||
| 17 | | 49ers | 539 | 11/23/1958 | @ | |||||||||||
| 18 | | 49ers | 533 | 9/24/1967 | vs | 180 | 34 | 5.3 | 3 | 353 | 22 | 16.0 | 2 | |||
| 19 | | 49ers | 532 | 9/18/1983 | @ | 191 | 31 | 6.2 | 1 | 341 | 20 | 17.1 | 3 | |||
| 20 | | 49ers | 531 | 10/8/1961 | vs | 259 | 40 | 6.5 | 4 | 272 | 20 | 13.6 | 1 | |||
| 21 | | 49ers | 530 | 12/8/1984 | vs | 184 | 40 | 4.6 | 3 | 346 | 25 | 13.8 | 3 | |||
| 22 | | 49ers | 526 | 10/14/1990 | @ | 50 | 24 | 2.1 | 0 | 476 | 32 | 14.9 | 6 | |||
| 23 | | 49ers | 524 | 11/17/1986 | @ | 83 | 18 | 4.6 | 0 | 441 | 33 | 13.4 | 0 | |||
| 24 | | 49ers | 521 | 12/11/1989 | @ | 63 | 25 | 2.5 | 1 | 458 | 30 | 15.3 | 3 | |||
| 25 | | 49ers | 521 | 11/12/1989 | vs | 235 | 47 | 5.0 | 2 | 286 | 17 | 16.8 | 3 | |||
BAL
NYJ
RAM
WAS
CHI
STLMore 49ers Stats
Team Leaders 
PASS
262
Purdy
RUSH
48
McCaffrey
REC
111
Robinson
Team Rankings
PPG
25.7
10th
OPP PPG
21.8
13th
RUSH YDS/G
106.9
24th
PASS YDS/G
254.0
6th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
