The San Francisco 49ers have a record of 21-15 against the Cardinals at home all-time.

Regular season

	TEAM	DATE	REC	TM		OPP	RESULT	W%	TD	1DWN	OFF	OPP OFF	3DWN%	4DWN%
1	49ers	11/18/1951	0-1	SF	vs	CHC	L 21-27	.000	3	26	379	437
2	49ers	9/29/1957	0-1	SF	vs	CHC	L 10-20	.000	1	16	324	346
3	49ers	9/27/1964	0-1	SF	vs	STL	L 13-23	.000	1	14	235	296
4	49ers	9/22/1968	1-0	SF	vs	STL	W 35-17	1.000	5	22	395	228
5	49ers	10/6/1974	0-1	SF	vs	STL	L 9-34	.000	1	12	306	407
6	49ers	11/12/1978	0-1	SF	vs	STL	L 10-16	.000	1	16	264	335
7	49ers	9/14/1980	1-0	SF	vs	STL	W 24-21	1.000	3	19	392	342
8	49ers	11/9/1986	1-0	SF	vs	STL	W 43-17	1.000	5	23	460	364
9	49ers	10/18/1987	1-0	SF	vs	STL	W 34-28	1.000	5	28	448	324
10	49ers	11/17/1991	1-0	SF	vs	PHX	W 14-10	1.000	2	22	257	176	60.0
11	49ers	10/24/1993	1-0	SF	vs	PHX	W 28-14	1.000	4	26	428	429	50.0
12	49ers	10/1/2000	1-0	SF	vs	ARI	W 27-20	1.000	3	18	345	365	43.8
13	49ers	10/27/2002	1-0	SF	vs	ARI	W 38-28	1.000	5	18	357	420	50.0	100.0
14	49ers	12/7/2003	1-0	SF	vs	ARI	W 50-14	1.000	7	30	496	210	50.0	0.0
15	49ers	10/10/2004	1-0	SF	vs	ARI	W 31-28	1.000	3	28	448	320	40.0	100.0
16	49ers	12/4/2005	0-1	SF	vs	ARI	L 10-17	.000	1	11	220	404	22.2
17	49ers	12/24/2006	0-1	SF	vs	ARI	L 20-26	.000	2	14	223	372	22.2	100.0
18	49ers	9/10/2007	1-0	SF	vs	ARI	W 20-17	1.000	2	16	194	261	25.0	100.0
19	49ers	9/7/2008	0-1	SF	vs	ARI	L 13-23	.000	1	13	291	285	37.5
20	49ers	12/14/2009	1-0	SF	vs	ARI	W 24-9	1.000	3	18	327	245	50.0
21	49ers	1/2/2011	1-0	SF	vs	ARI	W 38-7	1.000	5	16	362	279	18.2
22	49ers	11/20/2011	1-0	SF	vs	ARI	W 23-7	1.000	2	25	431	229	38.1	100.0
23	49ers	12/30/2012	1-0	SF	vs	ARI	W 27-13	1.000	3	20	407	262	28.6	100.0
24	49ers	10/13/2013	1-0	SF	vs	ARI	W 32-20	1.000	3	20	387	403	28.6	100.0
25	49ers	12/28/2014	1-0	SF	vs	ARI	W 20-17	1.000	2	18	395	397	41.7
	Average							.583	2.9	20.5	355.3	324.8
	Total		21-15					.583	103	739	12,791	11,691

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More 49ers Stats

Team Leaders

PASS

205

Purdy

RUSH

68

McCaffrey

REC

50

Robinson

Team Rankings

PPG

27.0

13th

OPP PPG

7.0

1st

RUSH YDS/G

174.0

4th

PASS YDS/G

205.0

18th

2026 Division Standings

TEAM	W	L	PCT
Cardinals	1	0	1.000
49ers	1	0	1.000
Seahawks	1	0	1.000
Rams	0	1	.000

Schedule

DATE	MATCHUP			TIME (ET)
Sun 9/20	MIA	@	SF	4:25 PM
Sun 9/27	ARI	@	SF	4:05 PM
Sun 10/4	DEN	@	SF	4:25 PM
Sun 10/11	SF	@	SEA	4:25 PM
Mon 10/19	WAS	@	SF	8:15 PM

Last Game

49ers

1 - 0

Final

Rams

0 - 1

Thu 10 Sep 2026

NFL 2026 Leaders

Pass Yards Leaders

410

Shough

387

Love

361

Young

Rush Yards Leaders

173

Walker

156

Gibbs

144

Henry

Rec Yards Leaders

182

Olave

150

Flowers

147

Watson

Pass TD Leaders

4

Lawrence

3

Shough

3

Dart

Rush TD Leaders

3

Swift

3

Henry

2

Williams

Rec TD Leaders

2

Jeanty

2

Watson

2

St. Brown

QB Rating Leaders

150.6

Lawrence

134.2

Dart

130.5

Allen

Sack Leaders

2.0

Hutchinson

2.0

Watt

2.0

Paye

NFL 2026 Rankings

PPG Rankings

59.0

41.0

39.0

37.0

36.0

34.0

Opp PPG Rankings

7.0

10.0

13.0

Total Yards Rankings

552.0

506.0

478.0

469.0

419.0

409.0

Rush Yards Rankings

291.0

220.0

202.0

174.0

165.0

Pass Yards Rankings

410.0

387.0

361.0

334.0

324.0

277.0

Sack Leaders

5.0

4.0

NFL Fantasy 2026

Fantasy RB Rankings

34.3

Henry

31.4

Swift

31.1

Walker

Fantasy WR Rankings

26.7

Watson

25.8

Coker

23.2

Jefferson

Fantasy TE Rankings

19.8

Likely

19.7

Goedert

15.5

McBride

Fantasy K Rankings

19

McPherson

16

Ryland

15

Sanders

NFL 2026 Betting

Best Record ATS

1-0

Worst Record ATS

0-1

NFL 2026 Standings

NFC East	W	L	T	PCT
Giants	1	0	0	1.000
Eagles	1	0	0	1.000
Commanders	0	1	0	.000
Cowboys	0	1	0	.000
NFC North	W	L	T	PCT
Vikings	1	0	0	1.000
Bears	1	0	0	1.000
Lions	1	0	0	1.000
Packers	0	1	0	.000
NFC South	W	L	T	PCT
Falcons	0	1	0	.000
Buccaneers	0	1	0	.000
Saints	0	1	0	.000
Panthers	0	1	0	.000
NFC West	W	L	T	PCT
49ers	1	0	0	1.000
Cardinals	1	0	0	1.000
Seahawks	1	0	0	1.000
Rams	0	1	0	.000

AFC East	W	L	T	PCT
Jets	1	0	0	1.000
Bills	1	0	0	1.000
Patriots	0	1	0	.000
Dolphins	0	1	0	.000
AFC North	W	L	T	PCT
Ravens	1	0	0	1.000
Bengals	1	0	0	1.000
Steelers	1	0	0	1.000
Browns	0	1	0	.000
AFC South	W	L	T	PCT
Jaguars	1	0	0	1.000
Texans	0	1	0	.000
Titans	0	1	0	.000
Colts	0	1	0	.000
AFC West	W	L	T	PCT
Chiefs	1	0	0	1.000
Raiders	1	0	0	1.000
Chargers	0	1	0	.000
Broncos	0	1	0	.000