The San Francisco 49ers are 11-6 against the NFC South in the regular-season and playoffs since 2017.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 9/10/2017 | 0-1 |  SF | vs |  CAR | L 3-23 | .000 | 0 | 13 | 217 | 287 | 18.2 | 25.0 |
| 2 | | 49ers | 11/25/2018 | 0-1 | SF | @ |  TB | L 9-27 | .000 | 1 | 23 | 342 | 412 | 12.5 | |
| 3 | | 49ers | 9/8/2019 | 1-0 | SF | @ | TB | W 31-17 | 1.000 | 3 | 17 | 256 | 295 | 38.5 | |
| 4 | | 49ers | 10/27/2019 | 1-0 | SF | vs | CAR | W 51-13 | 1.000 | 7 | 24 | 388 | 230 | 50.0 | |
| 5 | | 49ers | 12/8/2019 | 1-0 | SF | @ |  NO | W 48-46 | 1.000 | 6 | 25 | 516 | 465 | 50.0 | 100.0 |
| 6 | | 49ers | 12/15/2019 | 0-1 | SF | vs |  ATL | L 22-29 | .000 | 2 | 20 | 313 | 290 | 33.3 | 100.0 |
| 7 | | 49ers | 11/15/2020 | 0-1 | SF | @ | NO | L 13-27 | .000 | 1 | 21 | 281 | 237 | 43.8 | 0.0 |
| 8 | | 49ers | 12/19/2021 | 1-0 | SF | vs | ATL | W 31-13 | 1.000 | 4 | 23 | 397 | 275 | 54.5 | |
| 9 | | 49ers | 10/9/2022 | 1-0 | SF | @ | CAR | W 37-15 | 1.000 | 5 | 22 | 397 | 308 | 58.3 | |
| 10 | | 49ers | 10/16/2022 | 0-1 | SF | @ | ATL | L 14-28 | .000 | 2 | 21 | 346 | 289 | 37.5 | 0.0 |
| 11 | | 49ers | 11/27/2022 | 1-0 | SF | vs | NO | W 13-0 | 1.000 | 1 | 21 | 317 | 260 | 38.5 | 50.0 |
| 12 | | 49ers | 12/11/2022 | 1-0 | SF | vs | TB | W 35-7 | 1.000 | 5 | 24 | 404 | 322 | 44.4 | 50.0 |
| 13 | | 49ers | 11/19/2023 | 1-0 | SF | vs | TB | W 27-14 | 1.000 | 3 | 22 | 420 | 287 | 40.0 | 0.0 |
| 14 | | 49ers | 11/10/2024 | 1-0 | SF | @ | TB | W 23-20 | 1.000 | 2 | 24 | 413 | 215 | 45.5 | |
| 15 | | 49ers | 9/14/2025 | 1-0 | SF | @ | NO | W 26-21 | 1.000 | 3 | 23 | 344 | 307 | 53.3 | |
| 16 | | 49ers | 10/12/2025 | 0-1 | SF | @ | TB | L 19-30 | .000 | 1 | 17 | 363 | 352 | 43.8 | 0.0 |
| 17 | | 49ers | 10/19/2025 | 1-0 | SF | vs | ATL | W 20-10 | 1.000 | 2 | 23 | 324 | 292 | 60.0 | |
| Average | .647 | 2.8 | 21.4 | 355.2 | 301.4 | 43.6 | 3.7 | ||||||||
| Total | 11-6 | .647 | 48 | 363 | 6,038 | 5,123 | 43.6 | 33.3 |
More 49ers Stats
Team Rankings
PPG
23.7
14th
OPP PPG
22.9
16th
RUSH YDS/G
94.8
28th
PASS YDS/G
267.0
3rd
Rams
Seahawks
Cardinals
CLE
TEN
IND
CHI
Patriots
Bills
Ravens
Steelers
Jaguars
Broncos
Chargers
Eagles
Cowboys
Packers
KC
NYJ
LV
DET
CIN
