| TEAM | DATE | ATS | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 9/12/2021 | 1-0 |  SF | -371 | @ |  DET | +285 | W 41-33 | -7.5 | +0.5 (Y) | 45 | +29 (O) | 5 | 21 | 442 | 430 | 33.3 | |
| 2 | | 49ers | 9/19/2021 | 1-0 | SF | -150 | @ |  PHI | +127 | W 17-11 | -3 | +3 (Y) | 49 | -21 (U) | 2 | 23 | 306 | 328 | 42.9 | 100.0 |
| 3 | | 49ers | 10/10/2021 | 0-1 | SF | +208 | @ |  ARI | -257 | L 10-17 | +5.5 | -1.5 (N) | 48.5 | -21.5 (U) | 1 | 19 | 338 | 304 | 27.3 | 20.0 |
| 4 | | 49ers | 10/31/2021 | 1-0 | SF | -210 | @ |  CHI | +172 | W 33-22 | -4.5 | +6.5 (Y) | 40 | +15 (O) | 3 | 21 | 467 | 324 | 40.0 | 100.0 |
| 5 | | 49ers | 11/21/2021 | 1-0 | SF | -290 | @ |  JAX | +233 | W 30-10 | -6.5 | +13.5 (Y) | 45.5 | -5.5 (U) | 3 | 25 | 333 | 200 | 50.0 | 100.0 |
| 6 | | 49ers | 12/5/2021 | 0-1 | SF | -143 | @ |  SEA | +122 | L 23-30 | -2.5 | -9.5 (N) | 44.5 | +8.5 (O) | 3 | 17 | 365 | 327 | 30.0 | 50.0 |
| 7 | | 49ers | 12/12/2021 | 1-0 | SF | -128 | @ |  CIN | +106 | W 26-23 | -1.5 | +1.5 (Y) | 49 | 0 (P) | 3 | 21 | 355 | 397 | 33.3 | |
| 8 | | 49ers | 12/23/2021 | 0-1 | SF | -175 | @ |  TEN | +147 | L 17-20 | -3.5 | -6.5 (N) | 45.5 | -8.5 (U) | 2 | 22 | 389 | 278 | 37.5 | 50.0 |
| 9 | | 49ers | 1/9/2022 | 1-0 | SF | +151 | @ |  LAR | -178 | W 27-24 | +3.5 | +6.5 (Y) | 46.5 | +4.5 (O) | 3 | 23 | 449 | 265 | 64.3 | |
| 10 | | 49ers | 1/16/2022 | 1-0 | SF | +153 | @ |  DAL | -181 | W 23-17 | +3.5 | +9.5 (Y) | 51 | -11 (U) | 2 | 21 | 341 | 307 | 46.2 | |
| 11 | | 49ers | 1/22/2022 | 1-0 | SF | +208 | @ |  GB | -254 | W 13-10 | +5.5 | +8.5 (Y) | 47 | -24 (U) | 1 | 12 | 212 | 263 | 36.4 | 0.0 |
| 12 | | 49ers | 1/30/2022 | 1-0 | SF | +155 | @ | LAR | -183 | L 17-20 | +3.5 | +0.5 (Y) | 45.5 | -8.5 (U) | 2 | 16 | 282 | 396 | 33.3 | |
| 13 | | 49ers | 9/11/2022 | 0-1 | SF | -285 | @ | CHI | +230 | L 10-19 | -6.5 | -15.5 (N) | 38 | -9 (U) | 1 | 17 | 331 | 204 | 47.1 | 0.0 |
| 14 | | 49ers | 9/25/2022 | 0-1 | SF | -123 | @ |  DEN | +102 | L 10-11 | -1.5 | -2.5 (N) | 45 | -24 (U) | 1 | 13 | 267 | 261 | 10.0 | |
| 15 | | 49ers | 10/9/2022 | 1-0 | SF | -261 | @ |  CAR | +211 | W 37-15 | -6 | +16 (Y) | 39.5 | +12.5 (O) | 5 | 22 | 397 | 308 | 58.3 | |
| 16 | | 49ers | 10/16/2022 | 0-1 | SF | -192 | @ |  ATL | +161 | L 14-28 | -3.5 | -17.5 (N) | 46 | -4 (U) | 2 | 21 | 346 | 289 | 37.5 | 0.0 |
| 17 | | 49ers | 10/30/2022 | 1-0 | SF | -107 | @ | LAR | -113 | W 31-14 | -1.5 | +15.5 (Y) | 42 | +3 (O) | 4 | 22 | 368 | 223 | 55.6 | |
| 18 | | 49ers | 11/21/2022 | 1-0 | SF | -442 | @ | ARI | +341 | W 38-10 | -9.5 | +18.5 (Y) | 43 | +5 (O) | 5 | 21 | 387 | 314 | 54.5 | |
| 19 | | 49ers | 12/15/2022 | 1-0 | SF | -181 | @ | SEA | +152 | W 21-13 | -3 | +5 (Y) | 42.5 | -8.5 (U) | 3 | 15 | 381 | 277 | 46.2 | |
| 20 | | 49ers | 1/1/2023 | 0-1 | SF | -472 | @ |  LV | +359 | W 37-34 | -10 | -7 (N) | 41 | +30 (O) | 4 | 27 | 454 | 500 | 50.0 | |
| 21 | | 49ers | 1/29/2023 | 0-1 | SF | +131 | @ | PHI | -155 | L 7-31 | +3 | -21 (N) | 44.5 | -6.5 (U) | 1 | 11 | 164 | 269 | 25.0 | 0.0 |
| Average | 2.9 | 2.7 | 19.5 | 351.1 | 307.8 | 41.8 | 3.3 | |||||||||||||
| Total | 13-8 | 56 | 410 | 7,374 | 6,464 | 41.8 | 33.3 |
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20.0
23rd
OPP PPG
18.8
7th
RUSH YDS/G
88.0
28th
PASS YDS/G
287.3
2nd
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| NFC East | W | L | T | PCT |
|---|---|---|---|---|
| Eagles | 4 | 0 | 0 | 1.000 |
 Commanders | 2 | 2 | 0 | .500 |
| NFC North | W | L | T | PCT |
| Lions | 3 | 1 | 0 | .750 |
| Packers | 2 | 1 | 1 | .625 |
| NFC South | W | L | T | PCT |
 Buccaneers | 3 | 1 | 0 | .750 |
| Falcons | 2 | 2 | 0 | .500 |
| NFC West | W | L | T | PCT |
| 49ers | 3 | 1 | 0 | .750 |
| Seahawks | 3 | 1 | 0 | .750 |
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