The San Francisco 49ers have a 6-7 record against the Cardinals in the regular season and playoffs at home since 2014.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 12/28/2014 | 1-0 | vs | W 20-17 | 1.000 | 2 | 18 | 395 | 397 | 41.7 | |||
| 2 | | 49ers | 11/29/2015 | 0-1 | vs | L 13-19 | .000 | 1 | 17 | 368 | 337 | 0.0 | 50.0 | ||
| 3 | | 49ers | 10/6/2016 | 0-1 | vs | L 21-33 | .000 | 3 | 25 | 286 | 288 | 28.6 | 100.0 | ||
| 4 | | 49ers | 11/5/2017 | 0-1 | vs | L 10-20 | .000 | 1 | 17 | 329 | 368 | 35.3 | 0.0 | ||
| 5 | | 49ers | 10/7/2018 | 0-1 | vs | L 18-28 | .000 | 3 | 33 | 447 | 220 | 58.8 | 50.0 | ||
| 6 | | 49ers | 11/17/2019 | 1-0 | vs | W 36-26 | 1.000 | 5 | 26 | 442 | 266 | 46.2 | 0.0 | ||
| 7 | | 49ers | 9/13/2020 | 0-1 | vs | L 20-24 | .000 | 2 | 18 | 366 | 404 | 18.2 | 0.0 | ||
| 8 | | 49ers | 11/7/2021 | 0-1 | vs | L 17-31 | .000 | 2 | 22 | 337 | 437 | 40.0 | |||
| 9 | | 49ers | 1/8/2023 | 1-0 | vs | W 38-13 | 1.000 | 5 | 21 | 311 | 255 | 46.2 | 0.0 | ||
| 10 | | 49ers | 10/1/2023 | 1-0 | vs | W 35-16 | 1.000 | 5 | 30 | 395 | 362 | 60.0 | 100.0 | ||
| 11 | | 49ers | 10/6/2024 | 0-1 | vs | L 23-24 | .000 | 2 | 22 | 384 | 358 | 54.5 | 0.0 | ||
| 12 | | 49ers | 9/21/2025 | 1-0 | vs | W 16-15 | 1.000 | 1 | 19 | 355 | 260 | 20.0 | 50.0 | ||
| 13 | | 49ers | 9/27/2026 | 1-0 | vs | W 36-30 | 1.000 | 5 | 23 | 437 | 365 | 62.5 | |||
| Average | .462 | 2.8 | 22.4 | 373.2 | 332.1 | 39.3 | 0.0 | ||||||||
| Total | 6-7 | .462 | 37 | 291 | 4,852 | 4,317 | 39.3 | 31.3 |
SF
ARIMore NFL News
Jaguars LT Anton Harrison to have arthroscopic knee surgery and will miss weeks, maybe months
Week 5 coaching blunders haunt NFL contenders, from Sirianni’s London slip to Harbaugh’s gaffe
Rams LT Alaric Jackson strikes Bills LB Bradley Chubb after OT game
Josh Allen racks up 331 yards and Bills outlast Rams with help from blocked FG for 37-34 win in OT
Vikings playing keen game of keep-away, with hefty possession time and NFL's top turnover rate
Lions needed clutch 4th-down conversions to spark their blowout of the Cardinals
More 49ers Stats
Team Leaders 
PASS
1,196
Purdy
RUSH
286
McCaffrey
REC
326
Evans
Team Rankings
PPG
30.8
3rd
OPP PPG
18.6
3rd
RUSH YDS/G
128.6
8th
PASS YDS/G
239.2
15th
Seahawks
Rams
WAS
ATL
LV
DAL
MIN
NFL 2026 Leaders
NFL 2026 Rankings
NFL Fantasy 2026
NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
3 | 1 | 1 | .700 | |
2 | 3 | 0 | .400 | |
2 | 3 | 0 | .400 | |
1 | 3 | 1 | .300 | |
| NFC North | W | L | T | PCT |
5 | 0 | 0 | 1.000 | |
3 | 2 | 0 | .600 | |
3 | 2 | 0 | .600 | |
3 | 2 | 0 | .600 | |
| NFC South | W | L | T | PCT |
2 | 2 | 0 | .500 | |
2 | 3 | 0 | .400 | |
1 | 4 | 0 | .200 | |
1 | 4 | 0 | .200 | |
| NFC West | W | L | T | PCT |
5 | 0 | 0 | 1.000 | |
3 | 2 | 0 | .600 | |
2 | 3 | 0 | .400 | |
1 | 4 | 0 | .200 |
Giants
Eagles
Packers
Lions
Bears
Panthers
Buccaneers
Saints| AFC East | W | L | T | PCT |
|---|---|---|---|---|
4 | 1 | 0 | .800 | |
3 | 2 | 0 | .600 | |
2 | 3 | 0 | .400 | |
0 | 5 | 0 | .000 | |
| AFC North | W | L | T | PCT |
4 | 1 | 0 | .800 | |
3 | 2 | 0 | .600 | |
3 | 2 | 0 | .600 | |
3 | 2 | 0 | .600 | |
| AFC South | W | L | T | PCT |
4 | 1 | 0 | .800 | |
2 | 3 | 0 | .400 | |
1 | 4 | 0 | .200 | |
0 | 5 | 0 | .000 | |
| AFC West | W | L | T | PCT |
4 | 0 | 0 | 1.000 | |
3 | 2 | 0 | .600 | |
3 | 2 | 0 | .600 | |
0 | 5 | 0 | .000 |
Bills
Patriots
Jets
Dolphins
Ravens
Browns
Steelers
Bengals
Jaguars
Colts
Texans
Titans
Chiefs
Broncos
Chargers