The San Francisco 49ers have a record of 5-6 against the Colts between October 5, 1986 and October 5, 2026.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 10/5/1986 | 1-0 | vs | W 35-14 | 1.000 | 5 | 16 | 358 | 323 | ||||
| 2 | | 49ers | 9/10/1989 | 1-0 | @ | W 30-24 | 1.000 | 3 | 24 | 404 | 344 | ||||
| 3 | | 49ers | 10/15/1995 | 0-1 | @ | L 17-18 | .000 | 2 | 21 | 269 | 257 | 50.0 | 0.0 | ||
| 4 | | 49ers | 10/18/1998 | 1-0 | vs | W 34-31 | 1.000 | 4 | 36 | 448 | 336 | 54.5 | |||
| 5 | | 49ers | 11/25/2001 | 1-0 | @ | W 40-21 | 1.000 | 5 | 16 | 340 | 491 | 22.2 | |||
| 6 | | 49ers | 10/9/2005 | 0-1 | vs | L 3-28 | .000 | 0 | 12 | 177 | 365 | 21.4 | 100.0 | ||
| 7 | | 49ers | 11/1/2009 | 0-1 | @ | L 14-18 | .000 | 2 | 16 | 295 | 410 | 20.0 | |||
| 8 | | 49ers | 9/22/2013 | 0-1 | vs | L 7-27 | .000 | 1 | 14 | 254 | 336 | 25.0 | 100.0 | ||
| 9 | | 49ers | 10/8/2017 | 0-1 | @ | L 23-26 | .000 | 2 | 23 | 402 | 447 | 28.6 | 100.0 | ||
| 10 | | 49ers | 10/24/2021 | 0-1 | vs | L 18-30 | .000 | 2 | 13 | 280 | 295 | 9.1 | |||
| 11 | | 49ers | 12/22/2025 | 1-0 | @ | W 48-27 | 1.000 | 6 | 28 | 440 | 312 | 63.6 | 100.0 | ||
| Average | .455 | 2.9 | 19.9 | 333.4 | 356.0 | ||||||||||
| Total | 5-6 | .455 | 32 | 219 | 3,667 | 3,916 |
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More 49ers Stats
Team Leaders 
PASS
1,007
Purdy
RUSH
218
McCaffrey
REC
244
Kittle
Team Rankings
PPG
30.5
2nd
OPP PPG
16.0
3rd
RUSH YDS/G
137.3
6th
PASS YDS/G
251.8
13th
Seahawks
Rams
Cardinals
WAS
ATL
LV
DAL
NFL 2026 Leaders
NFL 2026 Rankings
NFL Fantasy 2026
NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
2 | 2 | 0 | .500 | |
1 | 3 | 0 | .250 | |
| NFC North | W | L | T | PCT |
4 | 0 | 0 | 1.000 | |
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
2 | 2 | 0 | .500 | |
| NFC South | W | L | T | PCT |
2 | 2 | 0 | .500 | |
1 | 2 | 0 | .333 | |
1 | 2 | 0 | .333 | |
0 | 4 | 0 | .000 | |
| NFC West | W | L | T | PCT |
4 | 0 | 0 | 1.000 | |
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
1 | 3 | 0 | .250 |
Giants
Eagles
Vikings
Bears
Lions
Packers
Panthers
Saints
Buccaneers| AFC East | W | L | T | PCT |
|---|---|---|---|---|
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
1 | 3 | 0 | .250 | |
0 | 4 | 0 | .000 | |
| AFC North | W | L | T | PCT |
3 | 1 | 0 | .750 | |
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
2 | 2 | 0 | .500 | |
| AFC South | W | L | T | PCT |
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
0 | 4 | 0 | .000 | |
0 | 4 | 0 | .000 | |
| AFC West | W | L | T | PCT |
4 | 0 | 0 | 1.000 | |
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
0 | 4 | 0 | .000 |
Bills
Patriots
Jets
Dolphins
Browns
Ravens
Steelers
Bengals
Jaguars
Titans
Texans
Chiefs
Broncos
Chargers