The San Francisco 49ers lost to the Arizona Cardinals, 24 to 20, in Week 1 on September 13, 2020. With the loss, the 49ers moved to 0-1 on the season.
| TEAM | DATE | TM | OPP | RESULT | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 9/13/2020 | vs | L 20-24 | 2 | 18 | 366 | 404 | 18.2 | 0.0 | ||
| 2 | | 49ers | 9/12/2021 | @ | W 41-33 | 5 | 21 | 442 | 430 | 33.3 | |||
| 3 | | 49ers | 9/11/2022 | @ | L 10-19 | 1 | 17 | 331 | 204 | 47.1 | 0.0 | ||
| 4 | | 49ers | 9/10/2023 | @ | W 30-7 | 3 | 22 | 391 | 239 | 46.2 | 100.0 | ||
| 5 | | 49ers | 9/9/2024 | vs | W 32-19 | 2 | 24 | 401 | 266 | 46.2 | |||
| 6 | | 49ers | 9/7/2025 | @ | W 17-13 | 2 | 24 | 384 | 230 | 50.0 | 100.0 | ||
| 7 | | 49ers | 9/10/2026 | @ | W 27-7 | 3 | 23 | 379 | 290 | 58.3 |
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More 49ers Stats
Team Leaders 
PASS
1,460
Purdy
RUSH
350
McCaffrey
REC
420
Evans
Team Rankings
PPG
29.5
3rd
OPP PPG
18.3
4th
RUSH YDS/G
128.2
6th
PASS YDS/G
243.3
16th
ATL
LV
DAL
MIN
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NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
3 | 2 | 1 | .583 | |
2 | 4 | 0 | .333 | |
2 | 4 | 0 | .333 | |
1 | 4 | 1 | .250 | |
| NFC North | W | L | T | PCT |
5 | 0 | 0 | 1.000 | |
5 | 2 | 0 | .714 | |
4 | 2 | 0 | .667 | |
3 | 2 | 0 | .600 | |
| NFC South | W | L | T | PCT |
3 | 2 | 0 | .600 | |
2 | 4 | 0 | .333 | |
2 | 4 | 0 | .333 | |
1 | 5 | 0 | .167 | |
| NFC West | W | L | T | PCT |
6 | 0 | 0 | 1.000 | |
3 | 3 | 0 | .500 | |
2 | 4 | 0 | .333 | |
2 | 4 | 0 | .333 |
Giants
Eagles
Commanders
Bears
Packers
Panthers
Saints
Buccaneers| AFC East | W | L | T | PCT |
|---|---|---|---|---|
5 | 1 | 0 | .833 | |
4 | 3 | 0 | .571 | |
2 | 4 | 0 | .333 | |
0 | 5 | 0 | .000 | |
| AFC North | W | L | T | PCT |
4 | 2 | 0 | .667 | |
4 | 2 | 0 | .667 | |
4 | 2 | 0 | .667 | |
3 | 2 | 0 | .600 | |
| AFC South | W | L | T | PCT |
4 | 2 | 0 | .667 | |
2 | 4 | 0 | .333 | |
2 | 4 | 0 | .333 | |
1 | 5 | 0 | .167 | |
| AFC West | W | L | T | PCT |
5 | 0 | 0 | 1.000 | |
4 | 2 | 0 | .667 | |
3 | 3 | 0 | .500 | |
0 | 6 | 0 | .000 |
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