Thurman Thomas has gotten the most total touchdowns for the Bills in a Week-1 game, with 4 touchdowns against the Rams on September 6, 1992.
| NAME | TD | DATE | TM | OPP | RUSH TD | REC TD | RET TD | FGM | XPM | XP2 | SFTY | PTS | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | T. Thomas | 4 | 9/6/1992 | vs | 3 | 1 | 0 | 0 | 0 | 0 | 24 | |||
| 2 | | T. Henry | 3 | 9/8/2002 | vs | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 18 | ||
| 3 | | A. Reed | 3 | 9/5/1993 | vs | 0 | 3 | 0 | 0 | 0 | 0 | 18 | |||
| 4 |  | J. Allen | 2 | 9/7/2025 | vs | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 5 | | J. Allen | 2 | 9/8/2024 | vs | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 6 | | S. Chandler | 2 | 9/11/2011 | @ | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 7 | | T. Henry | 2 | 9/7/2003 | vs | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 8 | | A. Reed | 2 | 9/6/1998 | @ | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 9 | | T. Thomas | 2 | 9/1/1991 | vs | 1 | 1 | 0 | 0 | 0 | 0 | 12 | |||
| 10 | | R. Riddick | 2 | 9/13/1987 | vs | 1 | 1 | 0 | 0 | 0 | 0 | 12 | |||
| 11 | | J. Cribbs | 2 | 9/6/1981 | vs | 1 | 1 | 0 | 0 | 0 | 0 | 12 | |||
| 12 | | J. Holland | 2 | 9/13/1976 | vs | 0 | 2 | 0 | 0 | 0 | 0 | 12 | |||
| 13 |  | O.J. Simpson | 2 | 9/21/1975 | vs | 2 | 0 | 0 | 0 | 0 | 0 | 12 | |||
| 14 | | A. Rashad | 2 | 9/16/1974 | vs | 0 | 2 | 0 | 0 | 0 | 0 | 12 | |||
| 15 | | O.J. Simpson | 2 | 9/16/1973 | @ | 2 | 0 | 0 | 0 | 0 | 0 | 12 | |||
| 16 | | L. Watkins | 2 | 9/16/1973 | @ | 2 | 0 | 0 | 0 | 0 | 0 | 12 | |||
| 17 | | J.D. Hill | 2 | 9/17/1972 | vs | 0 | 2 | 0 | 0 | 0 | 0 | 12 | |||
| 18 | | M. Briscoe | 2 | 9/19/1971 | vs | 0 | 2 | 0 | 0 | 0 | 0 | 12 | |||
| 19 | | G. Bass | 2 | 9/13/1964 | vs | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 20 |  | J. Cook III | 1 | 9/7/2025 | vs | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 21 |  | D. Kincaid | 1 | 9/7/2025 | vs | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 22 | | K. Coleman | 1 | 9/7/2025 | vs | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 23 | | M. Hollins | 1 | 9/8/2024 | vs | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 24 |  | K. Shakir | 1 | 9/8/2024 | vs | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 25 |  | S. Diggs | 1 | 9/11/2023 | @ | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
RAM
NYJ
BAL
NYJResults may be incomplete. StatMuse has complete game-level data for touchdowns going back to the 1950 season.
More Bills Stats
Team Leaders 
PASS
3,668
Allen
RUSH
1,606
Cook
REC
719
Shakir
Team Rankings
PPG
27.9
6th
OPP PPG
22.3
12th
RUSH YDS/G
156.4
2nd
PASS YDS/G
232.6
18th
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NFL 2025 Rankings
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NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 13 | 3 | 0 | .813 |
 Bills - w | 11 | 5 | 0 | .688 |
 Dolphins - e | 7 | 9 | 0 | .438 |
 Jets - e | 3 | 13 | 0 | .188 |
| AFC North | W | L | T | PCT |
9 | 7 | 0 | .563 | |
8 | 8 | 0 | .500 | |
 Bengals - e | 6 | 10 | 0 | .375 |
 Browns - e | 4 | 12 | 0 | .250 |
| AFC South | W | L | T | PCT |
 Jaguars - x | 12 | 4 | 0 | .750 |
 Texans - x | 11 | 5 | 0 | .688 |
 Colts - e | 8 | 8 | 0 | .500 |
 Titans - e | 3 | 13 | 0 | .188 |
| AFC West | W | L | T | PCT |
 Broncos - y | 13 | 3 | 0 | .813 |
 Chargers - w | 11 | 5 | 0 | .688 |
 Chiefs - e | 6 | 10 | 0 | .375 |
 Raiders - e | 2 | 14 | 0 | .125 |
Steelers| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 5 | 0 | .688 |
 Cowboys - e | 7 | 8 | 1 | .469 |
 Commanders - e | 4 | 12 | 0 | .250 |
 Giants - e | 3 | 13 | 0 | .188 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 5 | 0 | .688 |
 Packers - w | 9 | 6 | 1 | .594 |
 Vikings - e | 8 | 8 | 0 | .500 |
 Lions - e | 8 | 8 | 0 | .500 |
| NFC South | W | L | T | PCT |
8 | 8 | 0 | .500 | |
7 | 9 | 0 | .438 | |
 Falcons - e | 7 | 9 | 0 | .438 |
 Saints - e | 6 | 10 | 0 | .375 |
| NFC West | W | L | T | PCT |
 Seahawks - x | 13 | 3 | 0 | .813 |
 49ers - x | 12 | 4 | 0 | .750 |
 Rams - w | 11 | 5 | 0 | .688 |
 Cardinals - e | 3 | 13 | 0 | .188 |
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