The Buffalo Bills had their highest point differential in a game versus the Browns on November 4, 1990, with a 42-point differential.
Interpreted as:
buffalo bills largest margin of victory in a regular-season game| TEAM | DIFF | DATE | TM | OPP | RESULT | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Bills | 42 | 11/4/1990 | @ | W 42-0 | 6 | 24 | 310 | 234 | ||||
| 2 | | Bills | 40 | 10/3/2021 | vs | W 40-0 | 4 | 26 | 450 | 109 | 41.7 | 50.0 | ||
| 3 | | Bills | 38 | 9/20/1992 | vs | W 38-0 | 5 | 24 | 380 | 140 | 50.0 | |||
| 4 | | Bills | 37 | 9/23/2024 | vs | W 47-10 | 6 | 25 | 388 | 239 | 54.5 | 100.0 | ||
| 5 | | Bills | 37 | 12/23/1989 | @ | W 37-0 | 5 | 28 | 441 | 200 | ||||
| 6 | | Bills | 36 | 10/13/1991 | vs | W 42-6 | 6 | 23 | 396 | 240 | 85.7 | |||
| 7 | | Bills | 35 | 10/9/2022 | vs | W 38-3 | 5 | 21 | 552 | 364 | 55.6 | |||
| 8 | | Bills | 35 | 9/19/2021 | @ | W 35-0 | 5 | 21 | 314 | 216 | 53.8 | 100.0 | ||
| 9 | | Bills | 35 | 11/24/2014 | vs | W 38-3 | 5 | 21 | 336 | 218 | 53.8 | 0.0 | ||
| 10 | | Bills | 35 | 11/1/1970 | @ | W 45-10 | 6 | 18 | 364 | 251 | ||||
| 11 | | Bills | 34 | 9/24/2023 | @ | W 37-3 | 4 | 20 | 386 | 230 | 60.0 | 0.0 | ||
| 12 | | Bills | 34 | 9/19/2022 | vs | W 41-7 | 5 | 23 | 414 | 187 | 38.5 | 66.7 | ||
| 13 | | Bills | 34 | 9/11/2011 | @ | W 41-7 | 5 | 23 | 364 | 213 | 50.0 | |||
| 14 | | Bills | 34 | 12/26/2004 | @ | W 41-7 | 5 | 27 | 441 | 189 | 64.3 | 0.0 | ||
| 15 | | Bills | 34 | 10/30/1994 | vs | W 44-10 | 5 | 17 | 357 | 266 | 35.7 | 0.0 | ||
| 16 | | Bills | 34 | 9/27/1992 | @ | W 41-7 | 5 | 23 | 490 | 265 | 50.0 | |||
| 17 | | Bills | 34 | 9/18/1966 | vs | W 58-24 | 8 | 25 | 508 | 313 | ||||
| 18 | | Bills | 33 | 9/6/1992 | vs | W 40-7 | 5 | 23 | 363 | 215 | 50.0 | |||
| 19 | | Bills | 33 | 10/3/1976 | vs | W 50-17 | 7 | 25 | 446 | 502 | ||||
| 20 | | Bills | 32 | 9/13/1981 | @ | W 35-3 | 5 | 26 | 430 | 147 | ||||
| 21 | | Bills | 31 | 10/26/2025 | @ | W 40-9 | 5 | 23 | 410 | 244 | 58.3 | |||
| 22 | | Bills | 31 | 11/11/2018 | @ | W 41-10 | 5 | 23 | 451 | 199 | 50.0 | 100.0 | ||
| 23 | | Bills | 31 | 9/7/2003 | vs | W 31-0 | 4 | 23 | 322 | 239 | 50.0 | 0.0 | ||
| 24 | | Bills | 31 | 11/11/1990 | vs | W 45-14 | 6 | 20 | 360 | 127 | ||||
| 25 | | Bills | 31 | 10/22/1989 | vs | W 34-3 | 4 | 22 | 343 | 154 | ||||
NYJ
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RUSH
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157
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Team Rankings
PPG
28.3
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OPP PPG
21.5
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RUSH YDS/G
159.6
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PASS YDS/G
234.2
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| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
