Roscoe Parrish gained the most all-purpose yards for the Bills in a Week-1 game in 2010, with 65 yards versus the Dolphins on September 12, 2010.
| NAME | YDS | DATE | TM | OPP | TD | RUSH YDS | RUSH TD | REC YDS | REC TD | KR YDS | KR TD | PR YDS | PR TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | R. Parrish | 65 | 9/12/2010 |  BUF | vs |  MIA | 1 | 0 | 0 | 35 | 1 | 0 | 0 | 30 | 0 |
| 2 | | S. Johnson | 40 | 9/12/2010 | BUF | vs | MIA | 0 | 0 | 0 | 40 | 0 | 0 | 0 | 0 | 0 |
| 3 | | L. Evans | 34 | 9/12/2010 | BUF | vs | MIA | 0 | 0 | 0 | 34 | 0 | 0 | 0 | 0 | 0 |
| 4 | | C.J. Spiller | 25 | 9/12/2010 | BUF | vs | MIA | 0 | 6 | 0 | 8 | 0 | 11 | 0 | 0 | 0 |
| 5 | | D. Nelson | 22 | 9/12/2010 | BUF | vs | MIA | 0 | 0 | 0 | 22 | 0 | 0 | 0 | 0 | 0 |
| 6 | | F. Jackson | 19 | 9/12/2010 | BUF | vs | MIA | 0 | 19 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 7 |  | M. Lynch | 13 | 9/12/2010 | BUF | vs | MIA | 0 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 8 | | T. Edwards | 12 | 9/12/2010 | BUF | vs | MIA | 0 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
More Bills Stats
Team Rankings
PPG
30.9
2nd
OPP PPG
21.6
11th
RUSH YDS/G
131.2
9th
PASS YDS/G
231.6
17th
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| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles | 14 | 3 | 0 | .824 |
 Commanders | 12 | 5 | 0 | .706 |
| NFC North | W | L | T | PCT |
 Lions | 15 | 2 | 0 | .882 |
 Vikings | 14 | 3 | 0 | .824 |
| NFC South | W | L | T | PCT |
 Buccaneers | 10 | 7 | 0 | .588 |
 Falcons | 8 | 9 | 0 | .471 |
| NFC West | W | L | T | PCT |
 Rams | 10 | 7 | 0 | .588 |
 Seahawks | 10 | 7 | 0 | .588 |
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