The Buffalo Bills have a record of 36-18 against the AFC East between February 11, 2017 and February 11, 2026.
| OPP DIVISION | REC | W% | GP | W | L | T | TD | PTS | PPG | OPP PTS | OPP PPG | 1DWN | 3DWN% | 4DWN% | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | AFC East | 36-18 | .667 | 54 | 36 | 18 | 0 | 163 | 1,380 | 25.6 | 1,021 | 18.9 | 1,189 | 43.5 | 49.2 |
| 2 | NFC South | 9-4 | .692 | 13 | 9 | 4 | 0 | 41 | 337 | 25.9 | 270 | 20.8 | 259 | 43.8 | 42.9 |
| 3 | AFC West | 14-4 | .778 | 18 | 14 | 4 | 0 | 58 | 486 | 27.0 | 368 | 20.4 | 377 | 46.3 | 52.9 |
| 4 | AFC North | 10-7 | .588 | 17 | 10 | 7 | 0 | 40 | 381 | 22.4 | 381 | 22.4 | 339 | 38.8 | 52.6 |
| 5 | AFC South | 9-9 | .500 | 18 | 9 | 9 | 0 | 45 | 401 | 22.3 | 348 | 19.3 | 343 | 41.7 | 53.8 |
| 6 | NFC North | 6-3 | .667 | 9 | 6 | 3 | 0 | 26 | 218 | 24.2 | 212 | 23.6 | 194 | 38.4 | 55.6 |
| 7 | NFC East | 7-3 | .700 | 10 | 7 | 3 | 0 | 33 | 262 | 26.2 | 162 | 16.2 | 228 | 50.0 | 50.0 |
| 8 | NFC West | 7-2 | .778 | 9 | 7 | 2 | 0 | 40 | 316 | 35.1 | 224 | 24.9 | 223 | 51.5 | 87.5 |
More Bills Stats
Team Leaders 
PASS
556
Allen
RUSH
163
Cook
REC
157
Shakir
Team Rankings
PPG
28.3
4th
OPP PPG
21.5
12th
RUSH YDS/G
159.6
1st
PASS YDS/G
234.2
13th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
