Ottis Anderson has the most rushing yards for the St. Louis Cardinals in a season, with 1,605 yards in his rookie season in 1979.
| NAME | RUSH YDS | SEASON | TM | GP | ATT | YPC | RUSH YDS/G | RUSH TD | REC YDS | REC | TRG | AVG | REC YDS/G | REC TD | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | O. Anderson | 1,605 | 1979 | 16 | 331 | 4.8 | 100.3 | 8 | 308 | 41 | 7.5 | 19.3 | 2 | ||
| 2 | | O. Anderson | 1,376 | 1981 | 16 | 328 | 4.2 | 86.0 | 9 | 387 | 51 | 7.6 | 24.2 | 0 | ||
| 3 | | O. Anderson | 1,352 | 1980 | 16 | 301 | 4.5 | 84.5 | 9 | 308 | 36 | 8.6 | 19.3 | 0 | ||
| 4 | | O. Anderson | 1,270 | 1983 | 15 | 296 | 4.3 | 84.7 | 5 | 459 | 54 | 8.5 | 30.6 | 1 | ||
| 5 |  | D. Johnson | 1,239 | 2016 | 16 | 293 | 4.2 | 77.4 | 16 | 879 | 80 | 120 | 11.0 | 54.9 | 4 | |
| 6 |  | E. James | 1,222 | 2007 | 16 | 324 | 3.8 | 76.4 | 7 | 204 | 24 | 38 | 8.5 | 12.8 | 0 | |
| 7 | | O. Anderson | 1,174 | 1984 | 15 | 289 | 4.1 | 78.3 | 6 | 611 | 70 | 8.7 | 40.7 | 2 | ||
| 8 | | E. James | 1,159 | 2006 | 16 | 337 | 3.4 | 72.4 | 6 | 217 | 38 | 61 | 5.7 | 13.6 | 0 | |
| 9 |  | J. Conner | 1,094 | 2024 | 16 | 236 | 4.6 | 68.4 | 8 | 414 | 47 | 55 | 8.8 | 25.9 | 1 | |
| 10 | | J. Otis | 1,076 | 1975 | 14 | 269 | 4.0 | 76.9 | 5 | 69 | 12 | 5.8 | 4.9 | 1 | ||
| 11 | | J. David Crow | 1,071 | 1960 | 12 | 183 | 5.9 | 89.3 | 6 | 462 | 25 | 18.5 | 38.5 | 3 | ||
| 12 | | G. Hearst | 1,070 | 1995 | 16 | 284 | 3.8 | 66.9 | 1 | 243 | 29 | 8.4 | 15.2 | 1 | ||
| 13 | | B. Wells | 1,047 | 2011 | 14 | 245 | 4.3 | 74.8 | 10 | 52 | 10 | 16 | 5.2 | 3.7 | 0 | |
| 14 | | A. Murrell | 1,042 | 1998 | 15 | 274 | 3.8 | 69.5 | 8 | 169 | 18 | 9.4 | 11.3 | 2 | ||
| 15 | | J. Conner | 1,040 | 2023 | 13 | 208 | 5.0 | 80.0 | 7 | 165 | 27 | 33 | 6.1 | 12.7 | 2 | |
| 16 | | R. Moore | 1,018 | 1993 | 16 | 263 | 3.9 | 63.6 | 9 | 16 | 3 | 5.3 | 1.0 | 0 | ||
| 17 | | S. Mitchell | 1,006 | 1985 | 16 | 183 | 5.5 | 62.9 | 7 | 502 | 47 | 10.7 | 31.4 | 3 | ||
| 18 | | M. Lane | 977 | 1970 | 14 | 206 | 4.7 | 69.8 | 11 | 365 | 32 | 11.4 | 26.1 | 2 | ||
| 19 |  | K. Drake | 955 | 2020 | 15 | 239 | 4.0 | 63.7 | 10 | 137 | 25 | 31 | 5.5 | 9.1 | 0 | |
| 20 | | D. Johnson | 940 | 2018 | 16 | 258 | 3.6 | 58.8 | 7 | 446 | 50 | 76 | 8.9 | 27.9 | 3 | |
| 21 |  | E. Smith | 937 | 2004 | 15 | 267 | 3.5 | 62.5 | 9 | 105 | 15 | 20 | 7.0 | 7.0 | 0 | |
| 22 | | J. Johnson | 926 | 1990 | 14 | 234 | 4.0 | 66.1 | 5 | 241 | 25 | 9.6 | 17.2 | 0 | ||
| 23 | | E. Ferrell | 924 | 1988 | 16 | 202 | 4.6 | 57.8 | 7 | 315 | 38 | 8.3 | 19.7 | 2 | ||
| 24 | | O. Matson | 924 | 1956 | 12 | 192 | 4.8 | 77.0 | 5 | 199 | 15 | 13.3 | 16.6 | 2 | ||
| 25 | | J. Otis | 891 | 1976 | 14 | 233 | 3.8 | 63.6 | 2 | 15 | 2 | 7.5 | 1.1 | 0 | ||
STL
PHX
CHCStatMuse has season-level data for rushing yards going back to the 1932 season.
More Cardinals Stats
Team Leaders 
PASS
3,366
Brissett
RUSH
333
Carter
REC
1,239
McBride
Team Rankings
PPG
20.9
23rd
OPP PPG
28.7
29th
RUSH YDS/G
93.1
31st
PASS YDS/G
256.1
5th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
